Hypertrophic Cardiomyopathy Clinical Trial
Official title:
Sahlgrenska University Hospital Cardiomyopathy Project: Mapping and Diagnosis of Cardiomyopathies to Enable Early and Specific Treatment
Verified date | November 2018 |
Source | Göteborg University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
This is a joint project by Sahlgrenska University Hospital: Sahlgrenska, Östra and Mölndal.
Our objective is to diagnose and map patients with well phenotyped cardiomyopathies (CMP)
including in depth clinical and molecular phenotyping to enable earlier and specific
treatment. The project will serve as:
1. resource for diagnostic and therapeutic trials
2. common biomaterial bank
3. resource for detailed molecular analyses on patients' biomaterials and patient specific
symptoms and examination results
Status | Enrolling by invitation |
Enrollment | 3000 |
Est. completion date | January 2029 |
Est. primary completion date | January 2028 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 99 Years |
Eligibility |
Inclusion Criteria: - Patients with primary cardiomyopathies including hereditary and inflammatory dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, left ventricular non-compaction cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, myocarditis, giant cell myocarditis, sarcoidosis and amyloidosis engaging the heart Exclusion Criteria: - Patient with other preexisting cardiac diseases such as significant valvular, ischemic or pericardial disease before they receive a cardiomyopathy diagnose - patients < 18 years |
Country | Name | City | State |
---|---|---|---|
Sweden | Göteborg University, Sahlgrenska Universitetssjukhuset | Göteborg |
Lead Sponsor | Collaborator |
---|---|
Göteborg University | Sahlgrenska University Hospital, Sweden |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Progression in biomarker NT-proBNP | 2018-2028 | ||
Other | Changes over time in presence of autoantibodies | 2018-2028 | ||
Other | Disease activity evaluated by positron-emissions-tomography computed tomography (PET-CT) | 2018-2028 | ||
Other | Disease activity evaluated by magnetic resonance imaging (MRI) | 2018-2028 | ||
Primary | Time to disease progression | 2018-2028 |
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