Hypertrophic Cardiomyopathy Clinical Trial
Official title:
An Integrative-omics Study to Identify New Biomarkers of Cardiomyopathy Patients in China
This is a multi-omics research of Chinese cardiomyopathies patients, aiming to determine genetic risk factor and serial biomarkers of cardiomyopathies in diagnosis and prognosis.
Identification of novel biomarkers is needed to improve the diagnosis and prognosis of
cardiomyopathy. Also,the marked variation of genes which is still unclear, may influence
clinical outcomes is determined in part by genetic heterogeneity of the systemic response to
pathological process.
Specific aim:
1. Proteomics, microRNA-seq and metabolomics will be to determine the correlation of
echocardiographic parameters of systolic and diastolic functional entry with circulating
molecules
2. Genomics will be to determine the association of clinical outcome
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