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Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM — VANISH  

Hypertrophic Cardiomyopathy Clinical Trial

Official title:
Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM

Clinical Trial Summary

The purpose of this trial is to determine whether treatment with valsartan will have beneficial effect in early hypertrophic cardiomyopathy (HCM) by assessing many domains that reflect myocardial structure, function and biochemistry.

Clinical Trial Description

This is a multicenter, double-blind, placebo-controlled Phase II, randomized clinical trial to assess the safety and efficacy of valsartan in attenuating disease evolution in early HCM. Sarcomere mutation carriers with asymptomatic or mildly symptomatic overt disease (NYHA class I-II), and mutation carriers without left ventricular hypertrophy (LVH) will be studied. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01912534
Study type Interventional
Source HealthCore-NERI
Contact
Status Completed
Phase Phase 2
Start date March 2014
Completion date July 2019
View Details
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