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NCT03846908 Clinical Trial

Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)

Hypertriglyceridemia Clinical Trial

Official title:
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03846908
Other study ID # MCT-HTG
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 1, 2019
Est. completion date March 31, 2021

Study information
Verified date September 2021
Source Ludwig-Maximilians - University of Munich
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for the oral fat challenge.

Recruitment information / eligibility
Status Completed
Enrollment 13
Est. completion date March 31, 2021
Est. primary completion date January 31, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - hypertriglyceridemia (150 mg/dl-900 mg/dl) Exclusion Criteria: - Lipid lowering drugs or indication for Lipid lowering drugs - LDL-cholesterol > 190 mg/dl - Diabetes mellitus

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• MCT
patients will receive fat load with MCT
• SFA
patients will receive fat load with SFA
• MUFA
patients will receive fat load with MUFA

Locations
Country Name City State
Germany University Munich Munich

Sponsors (1)
Lead Sponsor Collaborator
Ludwig-Maximilians - University of Munich

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary postprandial hypertriglyceridemia area under the curve following oral fat load 8 hours after fat meal
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