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NCT00437931 Clinical Trial

Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction

Hyperthyroidism Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00437931
Other study ID # 006-07-EMC
Secondary ID
Status Completed
Phase N/A
First received February 19, 2007
Last updated September 7, 2016
Start date February 2007
Est. completion date February 2008

Study information
Verified date September 2016
Source HaEmek Medical Center, Israel
Contact n/a
Is FDA regulated No
Health authority Israel: Ethics Commission
Study type Observational

Clinical Trial Summary

Overt hyperthyroidism and hypothyroidism are associated with inverted hemodynamic changes.Regional blood flow disturbances (including intrathyroidal) were also reported in these thyroid disorders. The purpose of this study is to investigate the thyroid vascularity and blood flow by Color Flow Doppler Sonography in patients with subclinical thyroid dysfunction

Description:

Color Flow Doppler Sonography (CFDS) has become in the last years an increasing procedure to assess the thyroid blood flow. Previous studies showed specific changes of thyroid blood flow in hyperthyroidism, Hashimoto's thyroiditis and thyroid nodules when investigated by CFDS. Subclinical hyperthyroidism and hypothyroidism are common laboratory findings, defined by normal thyroid hormones concentrations along with ,respectively,decreased or increase Thyroid stimulating hormone (TSH) level. We purpose to investigate thyroid vascularity by CFDS in patients with subclinical hyperthyroidism or hypothyroidism and compared them with euthyroid patients.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date February 2008
Est. primary completion date February 2008
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- patients with subclinical hypothyroidism or hyperthyroidism

- patients with thyroid nodules and normal thyroid function

Exclusion Criteria:

- patients who are taking thyroxine, antithyroid drugs, lithium or amiodarone

- patients who had thyroid surgery or radioiodine therapy

- patients with NYHA class 3 or 4 heart failure

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Israel Haemek Medical Center, Department of Radiology Afula

Sponsors (1)
Lead Sponsor Collaborator
HaEmek Medical Center, Israel

Country where clinical trial is conducted

Israel, 

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