Clinical Trials Logo

Hyperthyroidism clinical trials

View clinical trials related to Hyperthyroidism.

Filter by:

NCT ID: NCT03434067 Recruiting - Thyroidectomy Clinical Trials

The Application of Rapid PTH Test Paper in Operation of Hyperparathyroidism

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

The half-life of the parathyroid hormone is about 4min, blood pth test is use in operation to confirm that parathyroid tumor is removed. but the blood pth test is time consuming and unpractical in most of hospital. this study will compare the application of rapid PTH test paper in operation of hyperparathyroidism.PTH test were measured in operation in different way. it will test at the time of preoperation, 15 minutes after surgery, 1 hour after surgery and 24 hours after surgery. thus evaluate the reliability and accuracy of PTH test paper in evaluating the Miami principles with the linear relation of blood PTH and the PTH test paper method.

NCT ID: NCT03303053 Recruiting - Graves Disease Clinical Trials

Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism

ChoPS
Start date: May 11, 2017
Phase: Phase 3
Study type: Interventional

Hyperthyroidism is the second most common endocrine disorder in the world with Graves' disease being the commonest. Anti thyroid drugs including methimazole, carbimazole, and propylthiouracil are effective treatments but take in most cases between 6 to 8 weeks to achieve euthyroidism. This study aim to assess the efficacy of cholestyramine and prednisolone as adjunctive treatment to standard treatment in patients with overt hyperthyroidism in 4 weeks.

NCT ID: NCT02812888 Recruiting - Hyperthyroidism Clinical Trials

Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism

Start date: July 2016
Phase: N/A
Study type: Observational [Patient Registry]

Clustering of various metabolic parameters including abdominal obesity, hyperglycaemia, low high-density lipoprotein cholesterol, elevated triglycerides and hypertension have been used worldwide as metabolic syndrome to predict cardiometabolic risk. Thyroid dysfunction impacts on various levels of these components. Recent evidence from HepG2 cells indicates that betatrophin, also known as TD26/RIFL/lipasin/ANGPTL8/C19orf80, a secreted protein that regulates glucose, lipid metabolism, and energy homeostasis, is induced by T3. However, the role of betatrophin in hyperthyroid patients is unknown. The objective was to study serum betatrophin levels in hyperthyroid patients and the association of serum betatrophin levels with hyperthyroidism.

NCT ID: NCT02772705 Recruiting - Hyperthyroidism Clinical Trials

Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans

Start date: May 2016
Phase: N/A
Study type: Observational

The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).

NCT ID: NCT02203682 Recruiting - Autoimmune Diseases Clinical Trials

Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy

Start date: July 2014
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effects of subantimicrobial dose doxycycline (50 mg/d), administered for 12 weeks, on patients with mild Thyroid-Associated Ophthalmopathy (TAO).

NCT ID: NCT02017080 Recruiting - Clinical trials for Hypothyroidism in Pregnancy

Fetal Thyroid Ultrasound And Fetal Thyroid Hormones

Start date: January 2014
Phase: N/A
Study type: Observational

Non invasive methods: maternal antithyroid antibodies and ultrasound measurement of the fetal thyroid gland could be an important tool for detecting fetal thyroid dysfunction in mothers with autoimmune thyroid disease.

NCT ID: NCT01779817 Recruiting - Hyperthyroid Clinical Trials

Assessment of Intellectual, Psychological and Behavioural Developments Between 6 and 9 Years of the Children Born to Hyperthyroid Mothers During Their Pregnancy

EDIEMHYPER
Start date: February 2013
Phase: Phase 4
Study type: Interventional

1. MAIN OBJECTIVE : To assess the consequences of a maternal hyperthyroïd during pregnancy on intellectual development of the child from 6 to 9 years 2. SECONDARY OBJECTIVES : 1. To assess the consequences of a maternal hyperthyroïd during pregnancy on the capacities of attention, learning process and the degree of hyperactivity of the child from 6 to 9 years. 2. To study if it exist differences of intellectual development, capacities of attention, learning process, and degree of hyperactivity in the child from 6 to 9 years, born to hyperthyroid mother during pregnancy, according to: - the etiology of the maternal hyperthyroïd (transitory gestation hyperthyroid versus disease of Basedow), - the use or not of a anti-thyroid treatment, - the rate of TSH néonatal (measured with the blotter by tracking with J3 at all the new born ones).

NCT ID: NCT01376648 Recruiting - Hyperthyroidism Clinical Trials

Thyroid Hormones Effect on Brown Adipose Tissue

Start date: December 2009
Phase: N/A
Study type: Observational

Brown adipose tissue (BAT) is important in energy expenditure through thermogenesis although the regulatory factors are not well known in humans. There is evidence suggesting that the thyroid hormones affect BAT functions in lower mammals, but the effects of the thyroid hormones on BAT activity in humans are still unclear. The objective of this study was to investigate the effects of thyroid hormones on glucose metabolism of BAT and other organs in humans.

NCT ID: NCT00525122 Recruiting - Hyperthyroidism Clinical Trials

Treatment of M.Graves With Radioactive Iodine: Follow-up Study

Start date: September 2007
Phase: N/A
Study type: Observational

Hypothesis: What is the natural course after treatment with radioactive iodine in patients with hyperthyroidism? What are the determinants for the development of acute hypo- or hyperthyroidism after treatment with radioactive iodine without antithyroid drugs?

NCT ID: NCT00151723 Recruiting - Hyperthyroidism Clinical Trials

Does Radioiodine Treatment Prevent Atrial Fibrillation and Bone Loss in Endogenous Subclinical Hyperthyroidism?

Start date: April 2004
Phase: N/A
Study type: Interventional

Subclinical hyperthyroidism is defined as the presence of serum free thyroxine (T4) and triiodothyronine (T3) levels within the reference range and a reduced serum thyrotrophin (TSH) level. Evidence is accumulating that it has important clinical effects. The SUBstudy is a randomised, Dutch multicenter trial to study whether radioiodine treatment prevents the development of atrial fibrillation and prevents decreases in bone mineral density in patients with endogenous subclinical hyperthyroidism.