Effect of Heat Stress on Global LV Function in Anesthetized Humans

Status Completed

Clinical Trial Summary

Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest, despite a reduction in left ventricular volume at end diastole. The effect of heat stress has not been reported in patients receiving general anesthesia and the impact of general anesthesia on these findings is not known. Trans-esophageal echocardiography will be used to measure parameters important to both systolic and diastolic function at temperature intervals of 1°C in patients undergoing "Heated Intraoperative Peritoneal Chemotherapy" (HIPEC.) That general anesthesia will not alter the cardiovascular effects of increased temperature that has been reported in healthy, un-anesthetized humans is the hypothesis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Cardiac Functional Disturbances During Surgery
Fever
Hyperthermia

Clinical Trial Details

NCT number	NCT04553900
Study type	Interventional
Source	University of California, San Diego
Contact
Status	Completed
Phase	N/A
Start date	June 9, 2017
Completion date	December 6, 2019

View Details

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