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Clinical Trial Summary

The Neuroendoscopic, Trans-occipital Approach Evacuation of Acute Hypertensive Cerebral Hemmorrhage Combined Low-drainage Surgery: a Multi-center Clinical Trial


Clinical Trial Description

To evaluate the effect of different surgical approaches on the prognosis of patients with hypertensive intracerebral hemorrhage, hypertensive patients who met the diagnostic criteria of American guidelines for the treatment of adult spontaneous intracerebral hemorrhage (2015) were selected. The time from onset to admission was less than 8 hours. Blood routine examination, liver and kidney function, coagulation system, infectious diseases and other examinations were performed before operation, with emergency surgical indications, They were divided into two groups: transfrontal keyhole approach and transoccipital keyhole approach. Emergency endoscopic hematoma removal was performed. The patients were systematically evaluated and followed up at 1 week, 1 month, 3 months, 6 months and 12 months after operation to observe the improvement of consciousness, GCS score, postoperative rebleeding (appearance, bleeding volume, location, broken into ventricle, etc.), The prognosis was evaluated by ADL score, GCS score, gos score, modified Rankin scale, Mrs scale and ICH Score (GCS, hematoma volume, intraventricular hemorrhage, infratentorial source, patient age, etc.). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04957849
Study type Interventional
Source Shanghai Changzheng Hospital
Contact Lijun Hou, MD,PhD
Phone 86 21 81885671
Email houlijunsmmu@163.com
Status Not yet recruiting
Phase N/A
Start date January 1, 2022
Completion date June 30, 2025

See also
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Active, not recruiting NCT02472574 - Dose-effect Relationship of Rt-PA on ICH Evacuation Phase 2
Completed NCT03452722 - Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA
Not yet recruiting NCT00940745 - Modified Stereotactic Aspiration and Thrombolysis of Intracerebral Hemorrhage:a Multi-center Controlled Study N/A