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Clinical Trial Summary

The aim of this study is to evaluate whether the use of a commercially available standardized olive extract (Tensiofytol®) in individuals with elevated blood pressure 1. Leads to a clinically relevant reduction of blood pressure on the short term, 2. Leads to a clinically relevant reduction of cholesterol levels, especially LDL, 3. Leads to a change in oxidative stress biomarkers. Participants will be stratified by sex before randomization to one of the three treatments for 8 weeks: - Tensiofytol: 100 mg oleuropein and 20 mg hydroxytyrosol per day - Placebo All treatments have an identical shape and color and should be used in the same way (oral intake; 3 capsules/day during dinner). No dietary instructions are given and participants are asked not to change their dietary habits, nor to start other therapies (medication, supplements, slimming diets, extra physical activity, etc.) during their study period. Standardized questionnaires are used to obtain information on demographics, dietary habits and side effects. At baseline and after 8 weeks, 27 ml blood is drawn for various biological analyses, and blood pressure, BMI and waist circumference are measured.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04874961
Study type Interventional
Source Universiteit Antwerpen
Contact Stef Lauwers
Phone 003232655134
Email stef.lauwers@uantwerpen.be
Status Recruiting
Phase Phase 4
Start date May 20, 2021
Completion date December 2024

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