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A Study for the Identification of Biomarker Signatures for Early Detection of Pulmonary Hypertension (PH) — CIPHER  

Hypertension, Pulmonary Clinical Trial

Official title:
A Prospective, Multicenter Study for the Identification of Biomarker Signatures for the Early Detection of Pulmonary Hypertension (PH)

Clinical Trial Summary

The primary purpose of this study is to identify and develop biomarker signatures based on circulating micro ribonucleic acid (RNA) in the blood samples associated with high risk of pulmonary hypertension (PH) to assist in the diagnosis of PH; to estimate the sensitivity, specificity, positive predictive value, and negative predictive value of the biomarker signatures in identifying participants with PH by comparing the biomarker signatures to right heart catheterization (RHC) and to compare the sensitivity, specificity, positive predictive value, and negative predictive value of the biomarker signatures with the sensitivity, specificity, positive predictive value, and negative predictive value of transthoracic echocardiogram (TTE) in identifying participants with PH documented by RHC.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04193046
Study type Interventional
Source Janssen Research & Development, LLC
Contact
Status Completed
Phase Early Phase 1
Start date December 16, 2019
Completion date February 18, 2022
View Details
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