Hypertension Clinical Trial
— DEEPOfficial title:
Diuretic Effect Evaluation of Petroselinum Crispum (Parsley) in Hypertensive Patients (DEEP): Phase-I Clinical Trial
NCT number | NCT03468361 |
Other study ID # | IAU-DEEP |
Secondary ID | |
Status | Withdrawn |
Phase | N/A |
First received | |
Last updated | |
Start date | March 1, 2018 |
Est. completion date | January 31, 2020 |
Verified date | March 2020 |
Source | University of Science Malaysia |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The use of alternative therapy, particularly herbal treatment is becoming prevalent among
patients. Many herbs are in-use for various ailments such as diabetes, digestive problems,
fever, hepatitis and hypertension etc. The common belief is, herbs are safe and easy to
access as compared to conventional therapy, however, most of the studies reported different
side effects which may be toxic at times. These adverse effects are mostly due to incorrect
use or lack of patient education.
Parsley is a plant with antioxidant, diuretic and antimicrobial properties. Literature
reported use of parsley as a diuretic by different communities in throughout the world. In
vitro studies in animal have also reported the diuretic effect as well as proposed mechanisms
for the use of parsley as diuretic however none of the studies have been conducted to
investigate the diuretic effect of parsley in humans. This study aims to evaluate the
diuretic and hence antihypertensive effect of parsley in hypertensive patients.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | January 31, 2020 |
Est. primary completion date | December 31, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - Any male or female patients with hypertension and already using conventional medications i.e. antihypertensive drugs. The consent forms will be provided to the patients and only those patients which are willing to participate will be included in the study. Patients with more than 3 co-morbidities and at high-risk conditions will not be included in the study. Exclusion Criteria: - Geriatric, pregnant and lactating patients will not be included in the study. More important, patients on diuretic medications as well as diabetes, will also be excluded from the study. |
Country | Name | City | State |
---|---|---|---|
Saudi Arabia | College of Clinical Pharmacy | Dammam | Eastern Province |
Saudi Arabia | FAMCO | Khobar | Eastern |
Lead Sponsor | Collaborator |
---|---|
University of Science Malaysia | Imam Abdulrahman Bin Faisal University |
Saudi Arabia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in baseline mean Blood pressure at day 7, day 14 and 21 | For observing any change in mean blood pressure, a blood pressure monitor will be used to determine any variation in blood pressure in millimeters of mercury (mm of Hg). | For observing any change in mean blood pressure, a blood pressure monitor will be used to determine any variation in blood pressure in millimeters of mercury (mm of Hg). A total of four readings will be taken at baseline day 0, day 7, day 14 and day 21. | |
Primary | Change in baseline mean urinary output at day 7, day 14 and 21 | For observing any change in mean urinary output, a urine container will be used to determine any variation in urinary output in millimeters (ml). | For observing any change in mean urinary output a total of four readings will be taken at baseline day 0, day 7, day 14 and day 21. |
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