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Acute Effect of Agiotensin-(1-7) in Healthy and Hypertensive Subjects — Ang-(1-7)  

Hypertension Clinical Trial

Official title:
Acute Effect of Agiotensin-(1-7) on Bood Pressure and Heart Rate in Healthy and Hypertensive Subjects

Clinical Trial Summary

In the modern concept of Renin-angiotensin System, Angiotensin-(1-7) plays a key role and demonstrates promising therapeutic potential due to it is generally opposite effects to Angiotensin II. The aim is to evaluate the effect of Ang-(1-7) acute administration on systolic and diastolic blood pressure (SBP and DBP) and heart rate (HR) in healthy and hypertensive subjects.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03001271
Study type Interventional
Source Instituto de Cardiologia do Rio Grande do Sul
Contact
Status Active, not recruiting
Phase Phase 0
Start date January 2014
Completion date March 2017
View Details
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