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Renal Denervation to Improve Outcomes in Patients With End-stage Renal Disease

Hypertension Clinical Trial

Official title:
Renal Denervation to Improve Outcomes in Patients With End-stage Renal

Clinical Trial Summary

Sympathetic activation is a hallmark of end-stage renal disease and adversely affects cardiovascular prognosis. Hypertension is present in the vast majority of these patients and plays a key role in the progressive deterioration of renal function and in the exceedingly high rate of cardiovascular events. Selective catheter-based renal denervation has been shown to be safe and effective in attaining improved and sustained blood pressure control in patients with resistant hypertension and normal renal function. The investigators hypothesize that catheter-based renal denervation is a safe and effective intervention to achieve sustained reduction in sympathetic nerve activity, BP and target organ damage in hypertensive End-Stage Renal Disease (ESRD) patients, which will result in improved cardiovascular outcomes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02021019
Study type Interventional
Source Baker Heart and Diabetes Institute
Contact
Status Completed
Phase N/A
Start date January 2014
Completion date December 2022
View Details
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