Hypertension Clinical Trial
— SAMPLESOfficial title:
A Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples
In this randomized controlled trial, we will provide primary care physicians with free samples of highly effective generic cardiovascular medications. We will test whether this intervention will stimulate cost-effective prescribing, reducing drug costs and improving adherence to essential cardiovascular medications.
Status | Not yet recruiting |
Enrollment | 660 |
Est. completion date | April 2011 |
Est. primary completion date | April 2011 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Primary care physicians receiving an existing academic detailing program in Pennsylvania Exclusion Criteria: - Those with administrative policies stating they do not accept free samples |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Health Services Research
Country | Name | City | State |
---|---|---|---|
United States | Brigham and Women's Hospital | Boston | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Brigham and Women's Hospital |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Percentage of prescriptions filled for generic medications | 6 months after receipt of samples | No | |
Primary | Patient adherence - Amount of prescriptions actually filled (Proportion of Days Covered) within each class in the first year of use of an anti-hypertensive or lipid-lowering medication | in the year subsequent to patient initiation of an anti-hypertensive or lipid-lowering medication | No | |
Secondary | The sum of medication costs for all prescriptions used to treat either hypertension or hypercholesterolemia. | The year before and the year after provision of samples | No | |
Secondary | Guideline adherence - Proportion of patients who received first-line anti-hypertensive medications suggested by JNC-VII when medications are initiated. | In the 6 months after receipt of samples | Yes |
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