Clinical Trials Logo
  1. Home
  2. Hypertension
  3. NCT00738972
  4. Details
NCT00738972 Clinical Trial

Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)

Hypertension Clinical Trial

Official title:
Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients.

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00738972
Other study ID # MK-0653A-168
Secondary ID 2008_020
Status Terminated
Phase Phase 3
First received August 19, 2008
Last updated August 17, 2013
Start date January 2008
Est. completion date August 2010

Study information
Verified date August 2013
Source Fundación Lindavista del Corazón AC
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Evaluate pleiotropic effects of simvastatin in hypertensive patients.

Other known NCT identifiers
  • NCT00621127

Recruitment information / eligibility
Status Terminated
Enrollment 12
Est. completion date August 2010
Est. primary completion date August 2010
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Females Or Males Over 18 Years Old

- Patients With Systemic Arterial Hypertension Grade I And II According With The European Society Of Cardiology

- Left Ventricular hypertrophy Demonstrated By Echocardiography

- Mild To Moderated hypercholesterolemia

- Willing To Participate And Sign The Informed Consent Form (ICF)

Exclusion Criteria:

- Type 1 Or 2 Diabetes Mellitus

- Familiar hypercholesterolemia

- Low Density Lipoprotein-Cholesterol (LDL-C) > 190 mg/dl

- History Of Myocardial Infarction Or Stable Chronic Angina

- Triglycerides >250 mg/dl

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• valsartan
80 mg valsartan. Duration: 12 months. Tablets
• pravastatin
40 mg pravastatin. Duration: 12 months. Tablets
• simvastatin
40 mg simvastatin. Duration: 12 months. Tablets
• ezetimibe (+) simvastatin
ezetimibe (+) simvastatin 10/40 mg. Duration: 12 months. Tablets

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Fundación Lindavista del Corazón AC

Outcome
Type Measure Description Time frame Safety issue
Primary Left Ventricular Hypertrophy Reduction With Statins in Hypertensive Patients Left ventricular hypertrophy reduction was to be measured by echocardiography. 6 Month(s)
See also
  Status Clinical Trial Phase
Terminated NCT04591808 - Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia Phase 3
Recruiting NCT04515303 - Digital Intervention Participation in DASH
Completed NCT05433233 - Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension N/A
Completed NCT05491642 - A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses Phase 1
Completed NCT03093532 - A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities N/A
Completed NCT04507867 - Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III N/A
Completed NCT05529147 - The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
Recruiting NCT06363097 - Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
Recruiting NCT05976230 - Special Drug Use Surveillance of Entresto Tablets (Hypertension)
Completed NCT06008015 - A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers Phase 1
Completed NCT05387174 - Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period N/A
Completed NCT04082585 - Total Health Improvement Program Research Project
Recruiting NCT05121337 - Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension N/A
Withdrawn NCT04922424 - Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men Phase 1
Active, not recruiting NCT05062161 - Sleep Duration and Blood Pressure During Sleep N/A
Completed NCT05087290 - LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
Not yet recruiting NCT05038774 - Educational Intervention for Hypertension Management N/A
Completed NCT05621694 - Exploring Oxytocin Response to Meditative Movement N/A
Completed NCT05688917 - Green Coffee Effect on Metabolic Syndrome N/A
Recruiting NCT05575453 - OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure N/A