Hypertension Clinical Trial
Official title:
Impact of Ambulatory Blood Pressure Monitoring for Antihypertensive Treatment Guidance in Medical Outpatients: The Hyper-ABC Study
The purpose of this study is to determine whether in patients with arterial hypertension, treatment guidance using 24-hour blood pressure measurement results in better blood pressure control compared to treatment guidance using office blood pressure measurement.
Blood pressure control in arterial hypertension remains poor, despite the availability of
effective drug treatment. Therefore, strategies to increase blood pressure control are
urgently needed. 24 hour blood pressure is a better predictor of cardiovascular morbidity
and mortality than office blood pressure. Furthermore, the lower variability of measurements
over time of 24 hour blood pressure could allow better adjustment of antihypertensive
therapy. However, there are only scarce data about antihypertensive treatment adjustment
using 24 hour blood pressure instead of office blood pressure.
Aim: To test the hypothesis that a 24 hour blood pressure guided therapy is is more
effective in reaching blood pressure control when compared to conventional office blood
pressure guided therapy.
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