Hypertension Arterial Clinical Trial
Official title:
Hypertension and Cardiovascular Risk Associated With Obstructive Sleep Apnea in Adult in Guadeloupe (French West Indies)
The MAPA is the reference method to estimate the PA during the SAHOS. The MAPA can be
recommended over 48 hours: indeed, the PA falls at the beginning of every apnea then
increases gradually up to a pressif peak arising at the time of the ventilatoire resumption.
These variations arise under the influence of 4 stimulus: the désaturation in O2, the rise of
the PaCO2, the increase of the respiratory effort and the microawakening of the end of apnea
who are at the origin of a sympathetic stimulation.
Consequently a better diagnostic approach of the HTA (confirmation of a resistant HTA, an
identification of the masked HTA and the patients " not dipper " by the MAPA), the
identification of the SAHOS, and a better coverage) of the associated cardiovascular risk
factors are essential and establish a stake in public health.
To investigator's knowledge, no datum or study on the association HTA-SAHOS and its
consequences was until then realized in the French overseas departments.
In Guadeloupe, data on the relationships between arterial hypertension and obstructive sleep apnea are unavailable. The aim of this study was: to assess the frequency of hypertension and non-dipper pattern evaluated by 48-hour ambulatory blood pressure monitoring in an adult population identified obstructive sleep apnea/non-obstructive sleep apnea during overnight polygraphy ; to determine the cardio-metabolic factors associated with obstructive sleep apnea. ;
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