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Hyperplasia clinical trials

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NCT ID: NCT01218243 Completed - Clinical trials for Benign Prostatic Hyperplasia (BPH)

An Efficacy Trial of Electroacupuncture at Points of Bilateral BL33 for Mild and Moderate Benign Prostatic Hyperplasia

Start date: September 2010
Phase: Phase 2
Study type: Interventional

To evaluate efficacy of BL33 for mild and moderate benign prostatic hyperplasia(BPH).There are trials showing that electroacupuncture on BL33 for mild and moderate BPH is more effective than terazosin. It could reduce the International Prostate Syndrome Score (IPSS) by 6.68±2.84(39.79%),lower urinary symptoms bother of score(BS) and bladder residual urine, and increase maximum urinary flow rate.But the efficacy of BL33 has not been studied. The objective of this study is to evaluate efficacy of BL32 for mild and moderate BPH by comparison with non-acupoint group.

NCT ID: NCT01184651 Completed - Clinical trials for Congenital Adrenal Hyperplasia

Tweens to Teens Project at Penn State

T2T@PSU
Start date: August 2009
Phase: N/A
Study type: Observational

The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development). The investigators will study girls with congenital adrenal hyperplasia (CAH) aged 10 to 13 to learn more about the girls' interests and activities, thoughts and feeling about being female, and family relationships. This will help investigators to understand the ways in which gender development is shaped by hormones and family relationships.

NCT ID: NCT01183650 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Study of Tadalafil in Benign Prostatic Hyperplasia

Start date: July 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the pharmacokinetics of tadalafil in Japanese and non-Japanese men with Benign Prostatic Hyperplasia (BPH). The safety of tadalafil will also be studied.

NCT ID: NCT01152190 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Study in Benign Prostatic Hyperplasia

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to evaluate the effect of tadalafil 5 milligrams (mg) daily for 8 weeks compared to placebo on prostatic blood perfusion in men with signs and symptoms of Benign Prostatic Hyperplasia (BPH), measured by resistive index (RI) in the prostate transition zone.

NCT ID: NCT01140178 Completed - Dysplasia Clinical Trials

A Trial of Photodynamic Therapy With HPPH for Treatment of Dysplasia, Carcinoma in Situ and T1 Carcinoma of the Oral Cavity and/or Oropharynx

Start date: June 8, 2010
Phase: Phase 1
Study type: Interventional

Recent literature suggests that certain patients with squamous cell cancers of the head and neck region may benefit from photodynamic therapy whether or not they may have received prior therapy, e.g. radiation therapy

NCT ID: NCT01139762 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary Symptoms

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of once daily tadalafil when taken with finasteride as a treatment for men with signs and symptoms of Benign Prostatic Hyperplasia and demonstrable prostate enlargement.

NCT ID: NCT01135888 Completed - Clinical trials for X-Linked Hypohidrotic Ectodermal Dysplasia

Short Term Effects and Risks of Physical Exercise in Subjects With Hypohidrotic Ectodermal Dysplasia

Start date: April 2009
Phase:
Study type: Observational

Because of their lack of sweat glands individuals with hypohidrotic ectodermal dysplasia (HED) are at particular risk of life-threatening hyperthermia during exercise in a warm environment. In this study, the effects of physical exercise are investigated in boys and male adolescents with X-chromosomally inherited HED as well as age-matched controls, who undergo standardized exertion on a bicycle ergometer at ambient temperatures of 25°C and 30°C. Body core temperature during and after ergometry, heart rate, performance, and serum lactate as a marker of metabolic stress are measured. Subjects with HED are expected to show an endangering rise of body temperature in connection with physical exercise. To clarify, whether novel cooling devices may reduce the likelihood of overheating, the effects of such devices are evaluated at 30°C.

NCT ID: NCT01133041 Completed - Colonoscopy Clinical Trials

Comparative Study of Postprocessing Imaging Systems for Diminutive Colonic Polyps

Start date: May 2010
Phase: Phase 4
Study type: Interventional

Several novel imaging technologies are currently used for detection and differentiation of colonic polyps during colonoscopy, such as NBI (Olympus), FICE (Fujinon), and i-Scan (Pentax). Several previous studies have indicated that NBI without magnification can be useful for real-time differentiation of diminutive colonic neoplasias. To date, however, there are no studies comparing NBI with other imaging systems (FICE or i-Scan) for differentiation of diminutive colonic polyps. The study objectives are to compare the diagnostic efficacy of NBI with that of i-Scan in real-time prediction of diminutive colonic polyps. In this prospective pilot study, diminutive colonic polyps detected during colonoscopy will be observed with conventional colonoscopy, thereafter will be observed with new imaging systems. Sensitivity, specificity, and diagnostic accuracy of both NBI and i-Scan will be assessed by reference to histological results obtained by endoscopic biopsy or polypectomy.

NCT ID: NCT01118260 Completed - Prostate Clinical Trials

Total Intravenous Anaesthesia (TIVA) Versus Spinal Anaesthesia in Patients Undergoing Transurethral Prostate Resection

TURPS
Start date: January 2006
Phase: Phase 4
Study type: Interventional

Comparison of total intravenous anaesthesia with spinal anaesthesia in patients undergoing transurethral prostate resection

NCT ID: NCT01111669 Completed - Clinical trials for Chronic Rhinosinusitis With Polyposis

Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery

Start date: August 2009
Phase: N/A
Study type: Interventional

Functional endoscopic sinus surgery (FESS) is an effective treatment of sinus disease. FESS is carried out using cameras to view the surgical field. Bleeding during the surgery can lead to poor surgical field visualization. Poor visualization has been associated with worse surgical outcomes. Tranexamic acid is a safe and effective agent used to achieve hemostasis during operative procedures. The current study is a randomized controlled trial in patients undergoing FESS to compare the effects of tranexamic acid versus placebo and the effects on surgical field visualization and adverse events.