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Hyperplasia clinical trials

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NCT ID: NCT04275076 Completed - Clinical trials for Prostate Hyperplasia

HoLEP Vs BPEP for Large Prostatic Adenoma

enucleation
Start date: February 1, 2018
Phase: Phase 3
Study type: Interventional

Benign prostatic hyperplasia (BPH) is one of the most common urinary disorders in elderly males. The symptoms of BPH include impaired physiological and functional well-being, which interferes with daily living. At present, transurethral resection of the prostate (TURP) is the standard surgical treatment. However, the high rate of complications associated with TURP is a major drawback of this procedure. Holmium laser enucleation of the prostate (HoLEP) was proven to be an effective surgical treatment for BPH with no prostate size limitation with adequate hemostasis, bipolar enucleation of the prostate (BPEP) has been introduced as an alternative energy source with a promising outcome with equal safety and efficacy

NCT ID: NCT04272216 Completed - Clinical trials for Benign Prostatic Hyperplasia

An Observational Study of Radial Access Embolization Procedures Using HydroPearl Microspheres

RAVI Registry
Start date: February 6, 2020
Phase:
Study type: Observational [Patient Registry]

This registry study is designed to collect data on the procedural success and complication rates in real-world patients undergoing HydroPearl embolization procedures via radial access.

NCT ID: NCT04271020 Completed - Clinical trials for Benign Prostatic Hyperplasia

Urodynamic Feasibility Study Utilizing the UroLift® System

UDS
Start date: October 25, 2018
Phase: N/A
Study type: Interventional

UDS evaluates the impact of Prostatic Urethral Lift (PUL) as measured by pressure flow, urodynamic testing (UDS) and an optional UroCuff Testing, an alternative urodynamic test. In addition, standard BPH measures such as symptoms, qualify of life, uroflowmetry, and post void residual will be evaluated at screening and at the follow-up visits.

NCT ID: NCT04267445 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Evaluate the Safety and Effectiveness of Using Echogenic Embolic Agent for Embolization of Prostate Artery for Treatment of Men With BPH (PAE CEUS)

PAE CEUS
Start date: March 2020
Phase:
Study type: Observational [Patient Registry]

A prospective single centre study to evaluate the safety and effectiveness of using contrast enhanced ultrasound and echogenic embolic agent Ekobi Embolization Microspheres in Prostate Artery Embolization for the Treatment of Men with Benign Prostatic Hyperplasia

NCT ID: NCT04266418 Recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

The Evaluation of Banana Flower Stamens Extract on Prevention of Benign Prostatic Hyperplasia in Adults

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

To assess the evaluation of banana flower stamens extract on prevention of benign prostatic hyperplasia in adults

NCT ID: NCT04263987 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial

Start date: January 1, 2020
Phase: Phase 3
Study type: Interventional

Holmium laser enucleation of the prostate (HOLEP) has proven to be efficacious and safe for the treatment of benign prostatic hypertrophy (BPH). New laser technologies such as the Moses Pulse laser system provide for improved energy delivery which may decrease blood loss and operative time. We seek to evaluate Moses technology for enucleation of the prostate in the setting of BPH.

NCT ID: NCT04255147 Active, not recruiting - Clinical trials for Bronchopulmonary Dysplasia

Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary Dysplasia

Start date: October 17, 2022
Phase: Phase 1
Study type: Interventional

Bronchopulmonary dysplasia (BPD) is a common and chronic lung disease that occurs in preterm infants following ventilator and oxygen therapy and is associated with long-term health consequences. Preclinical research shows that mesenchymal stromal cells (MSCs) can modify a number of pathophysiological processes that are central to the progression of BPD and thus present as a promising new treatment option. The main purpose of this Phase I study is to evaluate the safety of human umbilical cord tissue-derived MSCs in extremely preterm infants at risk of developing BPD.

NCT ID: NCT04253418 Terminated - Skin Lesion Clinical Trials

Nano-Pulse Stimulation (NPS) in Sebaceous Hyperplasia Optimization Study

Start date: December 20, 2018
Phase: N/A
Study type: Interventional

Primary study objective is to evaluate the optimization of Nano-Pulse Stimulation (NPS) energy settings for lesion clearance of Sebaceous Hyperplasia (SH) lesions from facial areas of healthy adult subjects.

NCT ID: NCT04252001 Not yet recruiting - Clinical trials for Growth Hormone Deficiency

Growing up With the Young Endocrine Support System (YESS!)

YESS
Start date: December 1, 2024
Phase: N/A
Study type: Interventional

Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out of paediatric care. Non-attendance and sub-optimal medical self-management can lead to serious and expensive medical complications. In a pilot study, adolescents suggested the use of e-technology to become more involved in the transition process. The investigators have designed and developed the YESS! game, a tool to help improve medical self-management in adolescents with chronic endocrine disorders. The hypothesis is that adolescents playing the YESS! game will show a larger increase in self-management score during the first year of transition and will have a lower drop-out rate at the adult endocrine outpatient clinic (OPC), compared to adolescents who do not play the game.

NCT ID: NCT04245566 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Prostatic Artery Embolization vs. Pharmacotherapy for LUTS/BPH

EMPATHY
Start date: September 2021
Phase: Phase 3
Study type: Interventional

This study compares safety and efficacy of prostatic artery embolization and pharmacotherapy in the treatment of lower urinary tract symptoms associated wit benign prostatic hyperplasia.