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Hyperplasia clinical trials

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NCT ID: NCT03902080 Completed - Overactive Bladder Clinical Trials

Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

Start date: March 26, 2019
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy of vibegron compared with placebo in men with overactive bladder (OAB) symptoms on pharmacological therapy for benign prostatic hyperplasia (BPH) as defined by micturition and urgency episodes.

NCT ID: NCT03887871 Completed - Clinical trials for Benign Prostatic Hyperplasia

Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers After Meal

Start date: March 11, 2019
Phase: Phase 1
Study type: Interventional

This study is an open-label, randomized, fed, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tamsulosin HCl Tablet" and Astellas Phama Korea Inc. "Harnal-D" in healthy volunteers

NCT ID: NCT03887858 Completed - Clinical trials for Benign Prostatic Hyperplasia

Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers

Start date: March 11, 2019
Phase: Phase 1
Study type: Interventional

This study is an open-label, randomized, fasted, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tamsulosin HCl Tablet" and Astellas Phama Korea Inc. "Harnal-D" in healthy volunteers

NCT ID: NCT03856242 Completed - Clinical trials for Benign Prostatic Hyperplasia (BPH)

Benign Prostatic Hyperplasia and Ischemic Heart DIsease

Start date: September 1, 2015
Phase: Phase 4
Study type: Interventional

To examine the dynamics of 24 - hours ECG monitoring parameters (Holter monitoring) in patients with ischaemic heart disease (IHD) before and after treatment of voiding dysfunctions resulted from benign prostatic hyperplasia (BPH) with the indications for either conservative or operative treatment. A total of eighty-three 57-to-81-year-old (mean age 70.4±5.75 years) patients with BPH and accompanying IHD were examined at the Institute of Urology and Human Reproductive Health and Clinic of Cardiology of the Sechenov University.

NCT ID: NCT03845933 Completed - Clinical trials for Right Colon Hyperplastic Polyp Miss Rate

Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection. It will be a single-site study conducted in Taiwan.

NCT ID: NCT03829904 Completed - Clinical trials for Benign Prostatic Hyperplasia

The Effect of Traditional Chinese Medicine on Benign Prostatic Hyperplasia

Start date: March 6, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This randomized, double-blinded, placebo-controlled, crossover clinical trial aims to investigate the effect of VGH-BPH1, a scientific Chinese medicine powder prescription, on patients with benign prostatic hyperplasia.

NCT ID: NCT03814824 Completed - Clinical trials for Barrett's Esophagus Without Dysplasia

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

Start date: January 23, 2019
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial examining how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric laser endomicroscopy).

NCT ID: NCT03736512 Completed - Clinical trials for Benign Prostatic Hyperplasia (BPH)

China Greenlight Registry Study (Post-market)

Start date: February 27, 2019
Phase:
Study type: Observational [Patient Registry]

The duration of the study is expected to take approximately 3 years, which includes a recruitment period of approximately 12-months and 2 years (24-months) to complete procedure and follow-up visits.

NCT ID: NCT03718234 Completed - Clinical trials for Congenital Disorders

Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia

Start date: January 1, 2019
Phase: Phase 1
Study type: Interventional

This is an open-label, non-randomized crossover design feasibility trial comparing oral hydrocortisone treatment with interval bolus delivery (pulsatile) of subcutaneous hydrocortisone via infusion pump in children with congenital adrenal hyperplasia. Eight children, ages 4-18 yrs, will have 24-hr pharmacokinetic and pharmacodynamic profiles of cortisol, 17-hydroxyprogesterone and androstenedione concentrations while on oral hydrocortisone therapy (admission 1), during an initial trial of the subcutaneous hydrocortisone pump (admission 2), and after 6 weeks of subcutaneous hydrocortisone pump treatment (admission 3). An integrated pharmacokinetic and pharmacodynamic model will be used to determine cortisol, 17-hydroxyprogesterone and androstenedione parameters to compare the duration of time subjects have these concentrations outside acceptable ranges. Funding Source - FDA OOPD

NCT ID: NCT03687242 Completed - Clinical trials for Congenital Adrenal Hyperplasia

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Start date: September 6, 2018
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study of SPR001 for the treatment of classic CAH that will provide 12 weeks of open-label treatment to eligible subjects.