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NCT01857635 Clinical Trial

Use of TpCO2 (Transcutaneous CO2 Measurement) as PaCO2 Predictor During NIV in Case of Acute Hypercapnic Respiratory Failure

Hypercapnic Respiratory Failure Clinical Trial

— TpCO2-NIV  

Official title:
Use of TpCO2 (Transcutaneous CO2 Measurement)as PaCO2 Predictor During Non Invasive Ventilation (NIV) in Case of Acute Hypercapnic Respiratory Failure

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01857635
Other study ID # TpCO2-NIV
Secondary ID
Status Completed
Phase N/A
First received May 15, 2013
Last updated June 7, 2015
Start date February 2013
Est. completion date March 2015

Study information
Verified date June 2015
Source University of Lausanne Hospitals
Contact n/a
Is FDA regulated No
Health authority Switzerland: Laws and standards
Study type Observational

Clinical Trial Summary

In patients suffering from hypercapnic respiratory failure and treated by non invasive ventilation (NIV), the interest of using transcutaneous CO2 measurement to evaluate PaCO2 and PaCO2 variation over time is unknown and will be evaluated in this study. Measurements will be done during one-hour NIV treatments.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date March 2015
Est. primary completion date March 2015
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- ICU patient equipped with an arterial line

- NIV treatment prescribed by the clinician in charge

- Hypercapnia defined by PaCO2> 42mmHg

Exclusion Criteria:

- Severe hemodynamic instability

- Severe psychiatric disorders

- Denied consent

- Age < 18 years

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Switzerland Intensive care and burn unit, University hospital of Lausanne Lausanne

Sponsors (1)
Lead Sponsor Collaborator
University of Lausanne Hospitals

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Comparison between TpCO2 (transcutaneous non invasive CO2 partial pressure measurement) and PaCO2 (obtained by blood gas analysis) values during NIV treatment. sixty minutes No
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