Hydrocephalus Clinical Trial
Official title:
Brain Ultrasound in the Weaning of External Ventricular Leads
External Ventricular Deviation (EDV) is a medical device that provides transient and
controlled external drainage of cerebrospinal fluid (CSF). This device can also monitor
intracranial pressure (ICP). SEV is an emergency measure indicated for acute hydrocephalus
and / or intracranial hypertension (HTIC). Weaning from a DVE should be considered as soon as
possible from the moment the patient's clinical condition allows it. There is no consensus on
how to wean SEVs.
The main objective of this study is to evaluate inter and intraobserver reproducibility of
the measurement of the 3rd ventricle size by ultrasound in patients receiving a DVE
withdrawal test.
Ultrasound assessment of the ventricular system, including the size of the 3rd ventricle, can
be used in severe traumatic brain injury. Ultrasound measurement of the size of the 3rd
ventricle is used as a marker to monitor cerebral atrophy in neurodegenerative diseases such
as multiple sclerosis (MS). There is good correlation between brain ultrasound and MRI and CT
brain imaging to assess the size of the 3rd ventricle. Ultrasound measurement of the size of
the 3rd ventricle has never been evaluated in weaning external ventricular leads.
Measuring the size of the 3rd ventricle by ultrasound could be an interesting monitoring
technique during a SEV withdrawal trial to predict success or failure.
Weaning is usually based on a clamp test with more or less paraclinical clinical monitoring.
The recurrence of hydrocephalus and / or HTIC defines a withdrawal failure of the drainage
device.
The size of the 3rd ventricle evaluated by cerebral CT in a clamp test is found as a
predictor of weaning failure of a DVE.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06040697 -
Formative Usability Assessment of Wireless Thermal Anisotropy Devices
|
||
| Terminated |
NCT02408757 -
Sonographic Monitoring of Weaning of Cerebrospinal Fluid Drainages
|
||
| Terminated |
NCT01863381 -
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
|
N/A | |
| Completed |
NCT00652470 -
A Study Comparing Two Treatments for Infants With Hydrocephalus
|
Phase 2 | |
| Completed |
NCT00196196 -
A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.
|
Phase 3 | |
| Terminated |
NCT05501002 -
Pilot Study to Evaluate the CereVasc® eShunt® System in the Treatment of Communicating Hydrocephalus
|
N/A | |
| Active, not recruiting |
NCT05068128 -
Combined Flow and Pressure Study of Craniospinal Dynamic
|
||
| Completed |
NCT04496414 -
Bactiseal Catheter Safety Registry in China
|
||
| Terminated |
NCT02900222 -
Study of Choroid Plexus Cauterization in Patients With Hydrocephalus
|
N/A | |
| Recruiting |
NCT04099823 -
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
|
N/A | |
| Unknown status |
NCT02775136 -
An Evaluation of a Non-invasive Brain Monitor
|
N/A | |
| Completed |
NCT00692744 -
Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH)
|
N/A | |
| Recruiting |
NCT04758611 -
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)
|
N/A | |
| Completed |
NCT03595033 -
Hydrocephalus iPad-App Based Intervention Study
|
N/A | |
| Completed |
NCT04207229 -
CERTAS Programmable Valve Registry
|
||
| Terminated |
NCT01973764 -
Intraventricular Drain Insertion: Comparison of Ultrasound-guided and Landmark-based Puncture of the Ventricular System
|
N/A | |
| Completed |
NCT01976559 -
Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol
|
N/A | |
| Completed |
NCT02381977 -
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment
|
N/A | |
| Recruiting |
NCT06086561 -
Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device
|
N/A | |
| Recruiting |
NCT05910944 -
European Study of Prodromal iNPH
|