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Effect of Sweetness Intensity of a Sucrose Solution on Blood Glucose Regulation and Energy Intake

Hunger Clinical Trial

Official title:
Einfluss Der Süßintensität Einer Saccharose-Lösung Auf Die Blutglukoseregulation Und Energieaufnahme in Gesunden Männern

Clinical Trial Summary

The aim of the present study is to investigate the influence of the modulation of the sweetness intensity of a carbohydrate (sucrose)-containing solution on metabolic effects, in particular the regulation of blood glucose concentration and regulation of hunger & satiety.

Clinical Trial Description

The study is designed as a randomised cross-over intervention study with four interventions. The study investigates the influence of sweetness modulation by Rebaudioside M (sweetness enhancement) and Lactisol (sweetness inhibition) of a 10% sucrose solution, corresponding to the concentration of a regular soft drink, on blood glucose regulation (blood glucose concentration and regulating hormones) in healthy male volunteers. Furthermore, the study assesses ad libitum energy intake, individual feelings of hunger and satiety, metabolic responses to the interventions, and preference for sweet-tasting foods such as sugar and sweeteners. In addition, the participants' individual thresholds for sweet taste, as well as morphological markers for taste sensitivity and body composition will be recorded as potential influencing factors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04991714
Study type Interventional
Source University of Vienna
Contact
Status Completed
Phase Early Phase 1
Start date August 5, 2021
Completion date December 30, 2022
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