Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing

Hiv Clinical Trial

Official title:

Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04917575
• Other study ID #: NCR191708
• Status: Recruiting
• Phase: N/A
• Start date: June 24, 2021
• Est. completion date: September 2024

Study information

• Verified date: January 2024
• Source: George Washington University
• Contact: Amanda D Castel, MD,MPH
• Phone: 202-994-8325
• Email: acastel[@]gwu.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will aim to assess the acceptability, usability and efficacy of using state-of-the-art video game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24. AYA often lack awareness of their personal risk of contracting HIV and where to go for testing and care. This lack of awareness has contributed to poor uptake of HIV testing among AYA despite engagement in high risk behaviors. The goal of this project is to harness this strong motivation to play games to increase HIV testing. Previous games for behavior change have yielded early success for increasing target behaviors among their sample populations, yet research on increasing HIV testing among AYA through gaming has been limited. This intervention builds on prior formative work and is designed to offer AYA personally-tailored risk messages and supports their accessibility to HIV testing and prevention services through an innovative gaming approach that is sharable over social media with in-game rewards for sharing the game with peers. The specific aim of this study is to determine the efficacy of a life-simulation game in changing HIV testing, knowledge, and risk behaviors among AYA at risk for HIV.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 300
• Est. completion date: September 2024
• Est. primary completion date: September 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 13 Years to 24 Years

Eligibility

Inclusion Criteria:

• age 13-24

• self-reported HIV negative or unknown status

• self-reported ever sexually active

• resident of the DC metropolitan region which includes the District of Columbia, Maryland and Virginia for at least the next 6 months

• Is able to provide informed consent or assent

• able to complete all study procedures in English

• has own mobile phones and be willing to use them for the study.

Related Conditions & MeSH terms

• Hiv

Intervention

Other:
• Mobile Game
An enhanced life-simulation prototype of a playable interactive game to increase HIV testing.
• Mobile Application
A mobile application that will include basic information on HIV basics (e.g., routes of transmission, data on the epidemiology of HIV among youth), prevention information, and information on HIV testing and PrEP, as well as a link to the HIV risk estimator, and HIV testing and PrEP locators.

Locations

Country	Name	City	State
United States	George Washington University Milken School of Public Health	Washington	District of Columbia

Sponsors (2)

Lead Sponsor	Collaborator
George Washington University	Media Rez

Country where clinical trial is conducted

United States, 

References & Publications (1)

Castel AD, Wilbourn B, Trexler C, D'Angelo LD, Greenberg D. A Digital Gaming Intervention to Improve HIV Testing for Adolescents and Young Adults: Protocol for Development and a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2021 Jun 24;10(6):e29792. doi: 10.2196/29792. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	HIV testing	Self-reported HIV testing in the past 6 months	prior 6 months
Secondary	Intent to test for HIV	Intent to test will be assessed using a validated 6-point Likert scale	baseline, 1, 3, 6 months
Secondary	HIV knowledge	18-item scale	baseline, 1, 3, 6 months
Secondary	HIV risk perception and behaviors	8-item scale and perceived likelihood of getting infected (0-100%)	baseline, 1, 3, 6 months
Secondary	Knowledge of PrEP	Has participant heard of PrEP at specified time period	baseline, 1, 3, 6 months
Secondary	CDC risk estimator scores		baseline, 1, 3, 6 months
Secondary	Frequency of game use		1, 3, 6 months
Secondary	PrEP screening	ever been screened for PrEP eligibility	baseline, 1, 3, 6 months
Secondary	PrEP use/uptake	been prescribed/taken PrEP	baseline, 1, 3, 6 months
Secondary	PrEP locator use	Number of linkages to PrEP locator	baseline, 1, 3, 6 months
Secondary	Duration of game use		1, 3, 6 months
Secondary	Reasons for continued or discontinued use of game		1, 3, 6 months
Secondary	HIV locator use	Number of linkage to HIV testing locator	baseline, 1, 3, 6 months