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NCT05808803 Clinical Trial

Aberrant Myeloid Lineage Differentiation in HIV/AIDS Patients

HIV Infections Clinical Trial

Official title:
A Single-center, Retrospective Cohort Study of Aberrant Myeloid Lineage Differentiation in HIV/AIDS Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05808803
Other study ID # 05
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2016
Est. completion date January 31, 2022

Study information
Verified date January 2023
Source Zhongnan Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The investigators included 782 HIV-infected patients from January 2016 to October 2020 Zhongnan Hospital of Wuhan University, whose AIDS diagnosis criteria met the "AIDS Diagnosis and Treatment Guide (2018 edition)" of Chinese Medical Association.

Recruitment information / eligibility
Status Completed
Enrollment 782
Est. completion date January 31, 2022
Est. primary completion date October 31, 2020
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - HIV-infection Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Zhongnan Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary The proportion of granulocytes and granulocyte/macrophage progenitors in myelogram of HIV/AIDS patients Flow cytometric immunophenotyping of an EDTA-anticoagulated BM aspirate specimen was performed. A standard BM assay with erythrocyte cell lysis was used for all BM aspirate specimens. Flow cytometric analysis was conducted using a FACS Canto II flow cytometer (Becton Dickinson, Sunnyvale, CA, USA). 2020
Secondary Neutrophil counts in peripheral blood of HIV/AIDS patients Blood samples were drawn from patients undergoing routine diagnostic blood analysis at our institute by sterile venipuncture into tubes containing 5.4 mg of K2EDTA and analyzed by the automated hematology analyzer. 2020
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