HIV Infections Clinical Trial
Official title:
Randomised, Double Blind, Placebo-controlled Dose Ranging Trial to Determine the Antiviral Activity and Safety of Alovudine in Nucleoside-experienced HIV-infected Subjects Experiencing Virologic Failure
The primary objective was to determine the mean change in HIV viral load from baseline to
Week 4 compared with placebo after 4 weeks of treatment in highly experienced HIV-infected
patients.
Secondary objectives were to determine (1) the tolerability, hematologic and hepatic safety
of different doses of alovudine and (2) the effect of baseline nucleoside genotypic
susceptibility on virologic response after 4 weeks of alovudine administration
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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