HIV Infections Clinical Trial
Official title:
Observational Cohort of HIV Infected Adults and Children in the PHPT Network Hospitals in Thailand
Since 2004, the Thai Ministry of Public Health has massively scaled up antiretroviral
treatment programs to provide therapy to more than 80,000 patients with partial support of
the Global Fund to fight AIDS, Tuberculosis and Malaria (GFATM).
As access to HIV care continues to expand under the universal health coverage system, it is
important to document and analyze the efficacy, tolerance, toxicity and acceptability of
antiretroviral therapy within pilot treatment programs, to provide evidence based feedback
and recommendations to the national program and policy makers.
As Thailand is rapidly expanding access to antiretroviral treatments under the universal
health coverage system, it is crucial to document and learn from pilot antiretroviral
treatment programs, in particular the medical outcomes and logistical, and organizational
issues faced by hospital teams and patients in order to adapt the ARV delivery and monitoring
system to various local settings.
Specific objectives
1. Analyze data collected in patients participating in the PHPT antiretroviral treatment
program, in accordance to national and international guidelines, with no experimental
interventions.
2. To determine factors associated with treatment outcome including immune status,
virologic factors and antiretroviral drugs levels
3. To study the operational aspects of integrating comprehensive HIV care into the existing
care system with regards to new activities generated at the hospital level (counseling,
referral systems, biological monitoring), the impact on other health activities,
mobilization of human and financial resources, affordability and sustainability.
The population of the study consists of approximately 2,000 consenting HIV-infected patients,
including one-third of children, receiving HIV care as part of the GF-ATM or OXFAM Access to
Antiretroviral programs, presenting at any of the PHPT network hospitals.
;
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