HIV Infections Clinical Trial
Official title:
The Effectiveness of Antiretroviral Therapy in Reducing the Costs of HIV/AIDS
The purpose of this study is to determine the impact of anti-HIV treatment on the work attendance of employed people in South Africa. The study will enroll participants from a large manufacturing and distribution firm in South Africa.
Little is known about the economic benefits of providing antiretroviral therapy (ART) for
HIV infected patients in sub-Saharan Africa and other resource-limited areas. In South
Africa, an increasing number of private sector firms are providing access to ART for their
employees. One of the barriers to such action, however, is the lack of available information
on the success of ART in restoring workers to full productivity, retaining skilled employees
in the workforce, and reducing the costs of medical care and death and disability benefits.
HIV infected employees on ART may be absent from work less often than untreated HIV infected
employees, but more often than HIV uninfected employees. This study will collect data from
an independent HIV/AIDS disease treatment program and a large private sector employer in
Johannesburg, South Africa to estimate the benefits and costs for businesses to provide ART
to eligible employees.
The study will combine individual-level medical outcome and treatment cost data from the
treatment program with data on employee work attendance and retention in the workforce from
the participating employer. The work attendance of HIV infected employees enrolled in the
HIV/AIDS treatment program (index participants) who are either taking ART or receiving
pre-ART care will be compared with each other and with that of HIV uninfected employees.
There are no study visits associated with this study; all data will be collected from
medical records maintained by the HIV/AIDS treatment program and the participants' employer.
The financial costs and benefits of the treatment program for the participating company will
also be estimated.
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