Quantification of Tenofovir Alafenamide Adherence (QUANTI-TAF)

Status Active, not recruiting

Clinical Trial Summary

This study is being done to evaluate the relationship between adherence to antiretroviral therapy (ART) and HIV drug concentrations in persons living with HIV (PLWH) that are taking tenofovir alafenamide (TAF). Adherence will be measured with an ingestible biosensor (digital pill). Antiretroviral drug concentrations will be measured in different types of blood cells.

Clinical Trial Description

PLWH taking or initiating/re-initiating TAF will be recruited for a 16-week study. Upon entering the study, participants will be trained on the use the digital pill to objectively quantify adherence. Study participants already taking TAF will return every 4 weeks for a study visit where blood for drug concentrations will be obtained. Participants initiating/re-initiating TAF will return weekly for the first 4 weeks, at weeks 6 and 8, and every 4 weeks thereafter for a study visit where drug concentrations will be obtained. ;

Study Design

Related Conditions & MeSH terms

Acquired Immunodeficiency Syndrome
Adherence, Medication
HIV Infections
HIV/AIDS

Clinical Trial Details

NCT number	NCT04065347
Study type	Observational
Source	University of Colorado, Denver
Contact
Status	Active, not recruiting
Phase
Start date	November 21, 2019
Completion date	May 2025

View Details

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