Recovery After Fast Track THA / TKA

Hip and Knee Osteoarthritis Clinical Trial

— 0-21  

Official title:

Prospective Descripive Study of Subacute Function After Total Hip or Knee Arthroplasty

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02137655
• Other study ID #: H-3-2014-005
• Status: Completed
• Phase: N/A
• First received: May 12, 2014
• Last updated: March 8, 2016
• Start date: May 2014
• Est. completion date: February 2016

Study information

• Verified date: March 2016
• Source: Rigshospitalet, Denmark
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denamrk: The regional Committee on Biomedical Research Ethics
• Study type: Observational

Clinical Trial Summary

The development and implementation of "fast-track" principles in total knee and hip arthroplasty have resulted in early recovery and rehabilitation alongside a reduced length of hospital stay. This without a concomitant increase in morbidity or readmissions for medical or surgical complications and with reduced mortality. However, only little is known about function in the subacute period after arthroplasty, and there is a need for further data on physical and psychological functioning following discharge from hospital.This to ensure, that the positive results from the perioperative setting are carried forward in the subacute phase.

Description:

Data will be published in three papers:

1. "Physical function and related factors following discharge from THA and TKA" Luna IE, Kehlet H, Aasvang EK.

2. "Postoperative hypoxemia following fast-track hip and knee arthroplasty" Luna IE, Kehlet H, Aasvang EK.

3. "Cognitive dysfunction after fast-track hip- and knee arthroplasty - prevalence and related factors". Luna IE, Kehlet H, Aasvang EK.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 112
• Est. completion date: February 2016
• Est. primary completion date: February 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 55 Years to 75 Years

Eligibility

Inclusion Criteria:

• Primary total hip or knee arthroplasty

• Age 55 to 80 years

Exclusion Criteria:

• Deficient written or spoken danish

• Alcohol abuse (>21 U per week)

• Immunocompromised

• Anticoagulant therapy

• ASA class 4-5

• Functional impairment from psychological or neurological disease

• Sleepapnea

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Hip and Knee Osteoarthritis
• Osteoarthritis, Knee

Locations

Country	Name	City	State
Denmark	Gentofte hospital	Gentofte	Region hovedstaden
Denmark	Vejle Sygehus	Vejle	Region syd

Sponsors (2)

Lead Sponsor	Collaborator
Rigshospitalet, Denmark	Lundbeck Foundation

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain	VAS when walking	48 hours postoperatively	No