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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05988606
Other study ID # 21-02-4359
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date May 12, 2021
Est. completion date November 14, 2021

Study information

Verified date August 2023
Source University of Alabama, Tuscaloosa
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this repeated measures study is to evaluate acute work rate adjustments during high-intensity interval training (HIIT) in a hot and temperate environment in healthy and active adults when using target heart rate to prescribe the exercise intensity. The main questions it aims to answer are: - Will HIIT based on target heart rate in a hot environment result in increased cardiovascular (i.e., elevated recovery HR) and thermal strain compared to HIIT in a temperate environment? - Will work rate be lowered to a greater extent during HIIT in a hot environment compared to a temperate environment in order to maintain target heart rate? - Will maximal aerobic capacity (V̇O2max) decrease to a greater extent after HIIT in the heat compared to a temperate environment? Procedures: Participants will complete 5 trials on a cycle ergometer. Trial 1 (Control Visit): Participants (n = 7) will have their maximal heart rate and V̇O2max measured in a temperate environment (~22 °C, 40% RH). Experimental Trials 2-5: The order of the trials will be counterbalanced and randomly assigned to participants. - 15TEMP: Participants will cycle at 70% of their maximum heart rate for 8 minutes as a warm-up, followed by one round of HIIT. The HIIT protocol consists of 4 minutes at 90% of maximum heart rate followed by 3 minutes at 70% of maximum heart rate, totaling 15 minutes, in a temperate environment (~22 °C, 40% RH). After the HIIT session, a graded exercise test will measure V̇O2max. - 15HEAT: Similar to 15TEMP, but participants will perform the HIIT protocol in a hot environment (~35 °C, 40% RH). - 43TEMP: Participants will cycle at 70% of their maximum heart rate for 8 minutes as a warm-up, followed by the HIIT protocol repeated four times (4 minutes at 90% of maximum heart rate and 3 minutes at 70% of maximum heart rate), totaling 43 minutes, in a temperate environment (~22 °C, 40% RH). - 43HEAT: Similar to 43TEMP, but participants will perform the HIIT protocol in a hot environment (~35 °C, 40% RH).


Recruitment information / eligibility

Status Completed
Enrollment 7
Est. completion date November 14, 2021
Est. primary completion date November 14, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 39 Years
Eligibility Inclusion Criteria: - Participants were healthy males and females who are 18 to 39 years of age, recreationally active as defined by the American College of Sports Medicine, performing moderate-intensity aerobic exercise 30 min or more per session for at least 3 sessions per week for at least the past 3 months, and free of metabolic, cardiovascular, and renal disease Exclusion Criteria: - Individuals classified as needing medical clearance according to American College of Sports Medicine (ACSM) Guidelines were not allowed to participate. Needing medical clearance is defined by ACSM as 1) not being physically active and having known cardiovascular, metabolic, or renal disease and asymptomatic; 2) not being physically active and having any signs or symptoms suggestive of cardiovascular, metabolic, or renal disease; 3) participating in regular exercise and having known cardiovascular, metabolic, or renal disease and asymptomatic; or 4) participating in regular exercise and having any signs or symptoms suggestive of cardiovascular, metabolic, or renal disease .

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
15 minutes of high-intensity interval training
Participants completed an 8 min warm-up and 1 round of high-intensity interval training
43 minutes of high-intensity interval training
Participants completed an 8 min warm-up and 5 rounds of high-intensity interval training
Other:
Hot environment
Participants exercised in a hot environment, ~ 35 °C, ~40% relative humidity.
Temperate environment
Participants exercised in a temperate environment, ~ 22 °C, ~40% relative humidity.

Locations

Country Name City State
United States The University of Alabama Tuscaloosa Alabama

Sponsors (1)

Lead Sponsor Collaborator
University of Alabama, Tuscaloosa

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary Work rate adjustments In a hot and temperate environment by how much does work rate need to be adjusted to maintain target heart rate? From the first work interval (min 9-12) to the last work interval (min 37-40).
Secondary Cardiovascular strain In a hot and temperate environment by how much does heart rate in the recovery intervals increase? From the first recovery interval (min 13-15) to the last recovery interval (min 41-43).
Secondary Thermal Strain In a hot and temperate environment by how much do rectal temperature and skin temperature increase? From the first work interval (min 9-12) to the last work interval (min 37-40).
Secondary Maximal aerobic capacity In a hot and temperate environment by how much does maximal aerobic capacity decrease? The end of the 15 min trials compared to the end of the 43 min trials.
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