View clinical trials related to High Intensity Exercise.
Filter by:Despite the benefits of physical exercise, the population does not adhere to the recommended levels of physical activity. The reported difficulties in starting and maintaining a physical exercise program are attributed to personal barriers and lack of motivation. Thus, there is an urgent need for efficient intervention proposals to increase engagement in daily physical exercise. High-intensity interval training (HIIT) is a promising and economical method, aiming at the development of efforts at high, maximum or supramaximal intensity, based on several methods: calisthenics (using the body's own strength) resistance (heavy objects, bars or devices for high-repetition resistance activities) and traditional (exercise modalities such as running and cycling). Emotional regulation (ER) is essential for the psychosocial well-being of human beings and is defined as the ability to influence, experience and express emotions, being an action, conscious or not, that directly modulates emotions and alters their nature as the intensity and duration. Regular physical exercise has been attributed to a reduction in depression symptoms, an increase in emotional well-being and a reduction in negative feelings. In addition to physical exercise, the use of cognitive reassessment to regulate emotions was positively associated with a decrease in negative affect in psychopathological diagnoses.
The overall goal of the CYCLE-AD trial is to determine the role of long-term, high intensity exercise in slowing or delaying the onset of cognitive and AD-related brain changes in e4 carriers. Successful translation and demonstration of the effectiveness of a scalable home-based exercise intervention capable of slowing or delaying disease onset will transform AD treatment, improve patient outcomes and quality of life, and reduce health care costs.