Impact of Platinum-based Cancer Treatment on Endothelial Function

Status Completed

Clinical Trial Summary

In this research we investigate endothelial function in cancer patients who received platinum based chemotherapy.

Clinical Trial Description

The goal of the study is to evaluate endothelial function in patients with platinum-based versus non-platinum-based chemotherapy. Endothelial function was evaluated via Angioscan( the apparatus that evaluate the stiffness of vessels by pulse wave velocity) and serum levels of endothelial nitric oxide synthase (ENOS),endothelin1. Patients with gastrointestinal, ovarian, bladder and brest cancer would be included. Patients with malignancies were followed-up from 2 weeks to 3 month after start of chemotherapy, Medical records and hospital databases were searched for all the patients treated with different chemotherapy treatment for any kind of cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04681560
Study type	Observational
Source	I.M. Sechenov First Moscow State Medical University
Contact
Status	Completed
Phase
Start date	January 18, 2018
Completion date	January 20, 2020

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