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Herpes Simplex Infections clinical trials

View clinical trials related to Herpes Simplex Infections.

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NCT ID: NCT02715752 Completed - Clinical trials for Cytomegalovirus Infections

A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin

Start date: January 2016
Phase: N/A
Study type: Observational

This study measured the changes in health-related complaints by analyzing charts of individuals, who are infected with a latent virus, who have used Gene-Eden-VIR/Novirin.

NCT ID: NCT02579083 Completed - HIV Clinical Trials

Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV

VAST
Start date: January 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and pharmacokinetics of MB66, a monoclonal antibody film for vaginal application that is being developed to potentially reduce the transmission of herpes simplex virus (HSV) and human immunodeficiency virus (HIV).

NCT ID: NCT02270099 Completed - Clinical trials for Herpes Simplex Infections

Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic Subjects

Start date: December 2014
Phase: N/A
Study type: Observational

This clinical performance study is being conducted to evaluate the performance of the Aptima Herpes Simplex Viruses 1 & 2 assay for detection of herpes simplex virus (HSV) type 1 (HSV-1) and HSV type 2 (HSV-2) in swab samples prospectively collected from suspected HSV lesions. Specimens collected using swabs from viral transport medium (VTM)collection kits and Aptima swab collection kits will be evaluated.

NCT ID: NCT01429311 Completed - Atopic Dermatitis Clinical Trials

Interferon Responses in Eczema Herpeticum

ADRN-01
Start date: April 2011
Phase: N/A
Study type: Observational

Atopic dermatitis (AD) is a chronic skin disorder characterized by recurrent viral skin infections. A small subset of patients with AD suffer from disseminated viral infections, e.g., eczema herpeticum (ADEH+), after herpes simplex infection (HSV) or eczema vaccinatum (EV) after smallpox vaccination. Interferon gamma (IFNγ) plays a critical role in the innate and acquired immune responses by activating macrophages, enhancing natural killer cell activation, and promoting T cell differentiation, as well as regulating B cell isotype switching to immunoglobulin (Ig) G2a. Recent studies have demonstrated that IFNγ generation was significantly decreased after stimulation with HSV ex vivo. The purpose of this study is to determine if deficient IFNγ induction leads to susceptibility to HSV infection in ADEH+ patients.