Hernia, Inguinal Clinical Trial
Official title:
The Desarda and Lichtenstein Techniques in Primary Hernia Treatment in Adult Males: Randomised, Multicenter, Blinded Study.
Contemporary treatment of inguinal hernia is generally based on surgical methods with the use
of synthetic meshes. The implanted meshes however have some disadvantages: they increase the
risk of infection, tend to sustain inflammation process, can generate chronic pain and
fertility disorders, can move from the initial implantation site, increase costs of treatment
etc. The research to find any new hernioplasty without the use of meshes is still going on.
Desarda in 2002 year published his own results over hernia treatment with the use of external
oblique aponeurosis. These results were comparable with the effects of Lichtenstein
technique.
The initial assessment done in our own department revealed good clinical results after hernia
treatment with Desarda's method.
To make appropriate and objective clinical assessment of the Desarda's technique for primary
inguinal hernia treatment the randomized multicentre double blinded clinical trial (RCT) was
projected and conducted. Finally, 105 patients were included in the Desarda group and 103 in
the Lichtenstein group. Personal clinical follow up was made up to 3 years after operation.
Generally no statistically significant differences were found between these groups. The only
difference was higher rate of seroma after Lichtenstein technique and different pain
perception in both groups. To the summary it is clear that Desarda technique is quite
attractive and good proposition for operative hernia treatment without mesh. The RCT was done
with the use of SharePoint Portal Server (Microsoft) which seems to be appropriate for
clinical trials.
n/a
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