Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05591482 |
| Other study ID # |
zagazig 15 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
January 1, 2014 |
| Est. completion date |
June 1, 2022 |
Study information
| Verified date |
October 2022 |
| Source |
Zagazig University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Objective: Evaluation of our management of acute or chronic traumatic diaphragmatic hernia
repair with sutures or mesh.
Between January 2014 and January 2019, a retrospective study on 185 patients with acute and
chronic traumatic diaphragmatic hernias was carried out at the general surgery department of
Zagazig University. Results both during and after surgery were assessed.
Description:
Traumatic diaphragmatic hernias are the outcome of 0.8% to 6% of blunt trauma cases and more
than 17% of cases involving thoraco-abdominal-penetrating trauma (TDH) . Chronic traumatic
diaphragmatic herniation (CTDH) is a condition that can develop as a result of an enlargement
of a defect in the diaphragm brought on by a pressure difference between the thoracic cavity
and the abdominal cavity . It is possible that the rupture will not heal on its own due to
the inherent pressure difference that exists between the thorax and the abdomen as well as
the continuous movement of the diaphragm .
Due to the seriousness of the related organs' injuries, traumatic diaphragmatic rupture
presents a complex emergency and typically necessitates a high diagnostic suspicion. The
herniated structures may strangulate into the thoracic cavity, and the mortality rate may
increase considerably if the traumatic diaphragmatic hernia is not identified and treated in
the acute phase of the trauma . These patients may not be diagnosed until weeks, months, or
even years after the initial traumatic event, and they may present with acute symptoms
related to the cardiovascular system and the digestive tract. A high mortality rate is seen
in people with CTDH with viscera that have been strangulated.
Despite advancements in diagnostic technologies, 2.7 - 50% of patients still have a
misdiagnosis . Early, accurate diagnosis is now more common thanks to greater experience and
the emergence of imaging tools, particularly computed tomography (CT).
A limited number of researches describe acute and chronic traumatic diaphragmatic hernias in
terms of intraoperative and postoperative outcomes. To examine the intraoperative and
postoperative results of patients with traumatic diaphragmatic hernias repaired using either
suture repair or mesh repair in terms of morbidity, mortality rate, and incidence of
recurrence, the investigators have established a retrospective cohort analysis for the
current investigation.
