Hepatocellular Carcinoma Clinical Trial
Official title:
A Phase II Study Of Intrabucally Administered Electromagnetic Fields and Regorafenib as Second-line Therapy For Patients With Advanced Hepatocellular Carcinoma.
The primary goal of this study is to gather efficacy data concerning the progression-free survival rate with electromagnetic fields plus Regorafenib when compared to historical data with Regorafenib alone as a second-line therapy in patients with advanced hepatocellular carcinoma who have received any first line systemic therapy either standard of care Sorafenib or Lenvatinib or any experimental therapy. Patients who have received any treatment that includes either electromagnetic fields or Regorafenib will be excluded.
Primary Objective: To estimate progression-free survival rates. Secondary Objectives - To obtain information concerning the feasibility of administration of the proposed treatment, including patient participation in trials using the proposed treatment. - To evaluate safety and tolerability in this patient population. - To evaluate the effect on levels of alpha-fetoprotein. ;
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