Management of Spontaneous Ruptured Hepatocellular Carcinoma

Hepatocellular Carcinoma Clinical Trial

Official title:

Management of Spontaneous Ruptured Hepatocellular Carcinoma - Partial Hepatectomy and Prognosis: A Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03516890
• Other study ID #: Chenxp010
• Status: Completed
• Start date: January 1, 2005
• Est. completion date: December 1, 2017

Study information

• Verified date: April 2018
• Source: Huazhong University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To investigate the best treatment for hepatocellular carcinoma rupture

Description:

To investigate the best treatment for hepatocellular carcinoma rupture, transcatheter arterial embolization or partial hepatectomy. Furthermore, to discuss the choice of emergency or staged hepatectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 216
• Est. completion date: December 1, 2017
• Est. primary completion date: June 1, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 15 Years to 76 Years

Eligibility

Inclusion Criteria:

• Being diagnosed as hepatocellular carcinoma with tumor rupture; with complete data and without loss of follow-up

Exclusion Criteria:

• Without complete data; with loss of follow-up; not hepatocellular carcinoma based on pathological diagnosis

Related Conditions & MeSH terms

• Carcinoma
• Carcinoma, Hepatocellular
• Hepatocellular Carcinoma
• Rupture
• Rupture Liver
• Rupture, Spontaneous

Intervention

Procedure:
• Partial hepatectomy
Partial hepatectomy was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Huazhong University of Science and Technology

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overall survival of all patients	Overall survival difference between the partial hepatectomy group and the non-surgical group	5 years
Secondary	Postoperative peritoneal dissemination	Postoperative peritoneal dissemination diagnosed by imaging examination	5 years
Secondary	Recurrence-free survival of all patients	Recurrence-free survival difference between the partial hepatectomy group and the non-surgical group	5 years
Secondary	Overall survival of partial hepatectomy patients	Overall survival difference between the emergency partial hepatectomy group and the staged partial hepatectomy group	5 years
Secondary	Recurrence-free survival of partial hepatectomy patients	Recurrence-free survival difference between the emergency partial hepatectomy group and the staged partial hepatectomy group	5 years
Secondary	Overall survival of staged partial hepatectomy patients	Overall survival difference between the staged early partial hepatectomy group and the staged late partial hepatectomy group	5 years
Secondary	Recurrence-free of staged partial hepatectomy patients	Recurrence-free survival difference between the staged early partial hepatectomy group and the staged late partial hepatectomy group	5 years