Hepatocellular Carcinoma Clinical Trial
Official title:
Prediction of Lymph Node Metastasis in Hepatocellular Carcinoma and the Study of Individualized Radiotherapy
Objectives:
1. To further validate the predictive efficacy of our established microRNA prediction model
of HCC lymph node metastasis.
2. To establish a precise therapeutic mode of prophylactic radiation therapy in high-risk
patients with HCC with lymph node metastasis under the guidance of a microRNA prediction
model.
First, screening out patients who underwent hepatic tumor resection and pathologically
diagnosed as HCC .
Then，performing the detection of miR-145, miR-31 and miR-92a by using the HCC lymph node
metastasis microRNA correlation prediction model established in our previous study. The
patients are judged as high risk of lymph node metastasis and low risk Patients, then
high-risk patients under the condition of informed consent into the group, randomized into
treatment group and control groups.
Last, Patients enrolled in the treatment group were treated with radiotherapy and followed
up.
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