Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Syndrome

Hepato-Renal Syndrome Clinical Trial

Official title:
Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Acute Kidney Injury

Status Completed

Clinical Trial Summary

Hepatorenal syndrome is a functional renal impairment occurring in cirrhotic patients . It develops secondary to splanchnic arterial vasodilatation which decreases the effective blood volume, activate the renin-angiotensin-aldosterone system, and stimulate of sympathetic nervous system.This study aims to compare the efficacy of nor-epinephrine versus midodrine/ octreotide, together with intravenous albumin on renal functions of patients with hepatorenal acute kidney injury.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04522297
Study type	Interventional
Source	National Hepatology & Tropical Medicine Research Institute
Contact
Status	Completed
Phase	N/A
Start date	April 15, 2018
Completion date	January 23, 2020

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See also
	Status	Clinical Trial	Phase
	Completed	`NCT04273750` - RAI & HRS: Relationship Between Relative Adrenal Insufficiency and Failure of Treatment in Hepatorenal Syndrome
	Recruiting	`NCT06161766` - Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease
	Completed	`NCT03483272` - MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)