Hepatitis C Clinical Trial
Official title:
A Phase 1, Open-Label, Single-Sequence Study to Examine the Effect of Telaprevir on the Pharmacokinetics of Buprenorphine in Subjects on Stable Buprenorphine/Naloxone Maintenance Therapy
The purpose of this study is to investigate the drug-drug interaction potential between
telaprevir and buprenorphine/naloxone. An understanding of the interaction potential will
help to determine whether buprenorphine dose adjustments are necessary for patients who are
concomitantly treated with telaprevir.
Telaprevir, in combination with other antiviral agents, is being investigated for the
treatment of chronic hepatitis C virus infection. Buprenorphine/naloxone is used for
maintainance therapy in patients with opioid dependence.
n/a
Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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