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Clinical Trial Summary

A single center, open labeled phase I/IIa study to evaluate safety, tolerability and efficacy of a therapeutic hepatitis B vaccine in oral antiviral drug-treated chronic hepatitis B virus carriers


Clinical Trial Description

- Objectives: To explore the appropriate dose of a therapeutic hepatitis B vaccine through the evaluation of safety, tolerability, and efficacy - Subjects: Chronic hepatitis B carrier with normal ALT range - Study hypothesis: The immune tolerance break and strong immune responses in the chronic hepatitis B carrier could be achieved with therapeutic hepatitis B vaccine containing novel adjuvant ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02693652
Study type Interventional
Source CHA Vaccine Institute Co., Ltd.
Contact
Status Completed
Phase Phase 1/Phase 2
Start date October 28, 2014
Completion date August 22, 2017

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