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Hepatitis A clinical trials

View clinical trials related to Hepatitis A.

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NCT ID: NCT04525833 Recruiting - Clinical trials for Hepatocellular Carcinoma

Liver Disease and Other Systemic Diseases

Start date: January 1, 2020
Phase:
Study type: Observational

Examine the association of chronic liver diseases (including hepatitis B, hepatitis C, alcoholic liver disease, fatty liver, liver cirrhosis, and hepatocellular carcinoma) with other systemic diseases by retrospectively analyzing the data from the Hospital Database of Buddhist Tzu Chi Medical Foundation.

NCT ID: NCT04525690 Completed - Hepatitis C Clinical Trials

Improving Inpatient Screening for Hepatitis C

Start date: September 21, 2020
Phase: N/A
Study type: Interventional

This study will use a stepped-wedge cluster randomized clinical trial to evaluate a health system initiative to set defaults in the electronic health record admission order set to nudge inpatient hepatitis C (HCV) screening.

NCT ID: NCT04518553 Not yet recruiting - Chronic Hepatitis b Clinical Trials

Plasma Purification and Chronic Hepatitis B

Start date: March 23, 2021
Phase: N/A
Study type: Interventional

To compare the efficacy of nucleoside analogues (HA) alone and plasma purification +HA in reducing HBV viral load.

NCT ID: NCT04515797 Completed - Hepatitis C Clinical Trials

QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir

QUICK-CURE
Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

This is a single center study characterizing the experience of administration of 4 weeks of pan-genotypic DAA therapy in kidney transplantation to prevent the transmission of hepatitis C virus infection from an HCV-positive donor kidney to an HCV-negative recipient.

NCT ID: NCT04510246 Recruiting - Hepatitis C Clinical Trials

Link Hepatitis C Notifications to Treatment in Tasmania

Start date: September 8, 2020
Phase: N/A
Study type: Interventional

This project will utilise the notification process as a point of intervention to work with primary practitioners (GP) by contacting them directly when a notification of hepatitis C exposure is received by the Tasmanian department of Health (DoH). A designated role will exist within DoH of a specialist HCV health worker to contact GPs to provide supported assistance in the process of the follow up hepatitis C diagnoses with patients. The study will evaluate whether active follow up of providers with enhanced case management is effective in having patients linked to hepatitis C treatment compared to current standard of care of surveillance for new notifications. The study will also compare the cost-effectiveness of this approach compared to current standard of care after one of their patients is notified with a positive hepatitis C antibody result.

NCT ID: NCT04508907 Recruiting - Hepatitis C Clinical Trials

A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients

Start date: September 10, 2020
Phase: Phase 4
Study type: Interventional

This study is being done to determine the effectiveness of using a combination of two different drugs in preventing the transmission of HCV from a HCV positive donor to a HCV negative solid organ recipient.

NCT ID: NCT04507607 Recruiting - Chronic Hepatitis B Clinical Trials

Efficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B Infection

Start date: August 1, 2020
Phase: Early Phase 1
Study type: Interventional

The effectiveness of mother-to-child block of CHB in pregnant women in the middle and later stages of pregnancy has been recognized by the guidelines. TAF, as a newly marketed antiviral drug, has not been conclusively concluded in terms of its efficacy and postpartum safety in preventing mother-to-child transmission in pregnant women.Our purpose is to explore the TAF for CHB the curative effect of pregnant and postnatal security.

NCT ID: NCT04507269 Completed - Clinical trials for Hepatitis B, Chronic

Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China

Start date: August 18, 2020
Phase: Phase 2
Study type: Interventional

This study is to evaluate the safety, pharmacokinetics characteristics, and antiviral activities of multiple doses of VIR-2218 in adults with chronic HBV infection in mainland China.

NCT ID: NCT04503993 Completed - Hepatitis B Clinical Trials

Healthy Planet Hepatitis B

Start date: February 25, 2020
Phase: N/A
Study type: Interventional

This quality improvement project utilizes Epic Health Planet to increase screening for chronic hepatitis B through the creation of registries and ordering of hepatitis B laboratory panels.

NCT ID: NCT04501224 Recruiting - Chronic Hepatitis b Clinical Trials

The Efficacy and Safety of TAF vs Other NAs in Patients With LVL

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

Patients with chronic hepatitis B should maximize the inhibition of HBV replication, which could reduce the incidence of liver cancer and liver disease-related complications. However, after 96 weeks of treatment with the first-line drugs, entecavir or tenofovir disoproxil fumarate, a certain proportion of patients still had low levels of HBV replication. Tenofovir alafenamide fumarate is a newly marketed anti-hepatitis B drug that is currently considered to be non-inferior to tenofovir disoproxil fumarate and safer bone and renal effects. Therefore, this research was put forward to investigate whether tenofovir alafenamide fumarate replacement for hepatitis B had a higher virological response rate and safety in patients with low levels of virus after 48 weeks of treatment with entecavir and tenofovir disoproxil fumarate.