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Propofol/Dexmedetomidine Versus Desflurane Effects on Post Hepatectomy Hepatocellular Injury

Hepatectomy Clinical Trial

Official title:
Propofol/Dexmedetomidine Versus Desflurane Effects on Post Hepatectomy Hepatocellular Injury

Clinical Trial Summary

This study will compare the effects of propofol/dexmedetomidine versus desflurane for maintenance of general anesthesia on hepatocellular injury in patients undergoing partial hepatectomy.

Clinical Trial Description

Postoperative impairment of liver function is common after hepatectomy. It may be caused by surgical trauma, loss of hepatic mass, stress response, hepatic oxygen deprivation, infection and drug toxicity. Anesthetic agents used in general anesthesia for liver surgery have a big effect on hepatic blood flow, oxygen delivery and liver function This study will compare the effects of propofol/dexmedetomidine versus desflurane for maintenance of general anesthesia on hepatocellular injury in patients undergoing partial hepatectomy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05246371
Study type Interventional
Source Ain Shams University
Contact ola Lashin, Master
Phone 00201026034100
Email Ola.lashin@med.asu.edu.eg
Status Recruiting
Phase Early Phase 1
Start date June 1, 2021
Completion date November 2023
View Details
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