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Hemorrhage clinical trials

View clinical trials related to Hemorrhage.

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NCT ID: NCT05548530 Recruiting - Brain Hemorrhage Clinical Trials

Prognostic Analysis of Different Treatment Options for Cerebral Hemorrhage

Start date: January 1, 2014
Phase:
Study type: Observational

To analyze the influence of early hematoma morphology on hematoma expansion, optimize the treatment plan for cerebral hemorrhage, and guide the treatment of patients with cerebral hemorrhage in combination with clinical practice.

NCT ID: NCT05547360 Recruiting - Clinical trials for GastroIntestinal Bleeding

Analysis of Blood Metabolomics to Identify Potential Biomarkers of Gastrointestinal Bleeding

Start date: July 19, 2022
Phase:
Study type: Observational

Despite advances in gastrointestinal endoscopy and pharmaceuticals, gastrointestinal bleeding is still a significant emergency disease with a high mortality rate of 1.9-5 per 100 people due to excessive bleeding and shock. There are several indicators using pulse rate, blood pressure, hemoglobin, etc. to select patients who require endoscopic intervention, or hospitalization, but these are inaccurate and with a high false-positive rate and low specificity at 35-40%. Therefore, tests with high diagnostic accuracy for gastrointestinal bleeding patients are required and findings specific biomarkers for gastrointestinal bleeding are of great importance.

NCT ID: NCT05546957 Completed - Healthy Volunteer Clinical Trials

Assess Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban in Healthy Adult Participants

Start date: January 5, 2023
Phase: N/A
Study type: Interventional

The primary objective of the study is to determine whether aspirin alone or aspirin combined with various doses of rivaroxaban causes subclinical GI blood loss as determined by the HemoQuant assay. The secondary objective of the study is to evaluate the safety and tolerability of aspirin alone or in combination with rivaroxaban to healthy volunteers.

NCT ID: NCT05545475 Recruiting - Clinical trials for Anticoagulants and Bleeding Disorders

Safety of Anticoagulant Therapy After Tissue Glue for Gastric Varices

Start date: January 1, 2022
Phase:
Study type: Observational

This study aimed to clarify the safety of anticoagulant therapy after glue injection for cirrhotic variceal bleeding patients with portal vein thrombosis.

NCT ID: NCT05542043 Completed - Clinical trials for Postpartum Hemorrhage (PPH)

Risk Factors for Postpartum Hemorrhage in Patients With Histologically Verified Placenta Accreta

Start date: July 1, 2020
Phase:
Study type: Observational

This retrospective, monocentric study aims to examine risk factors for postpartum hemorrhage in women with histologically verified placenta accreta. Women with histologically verified placenta accreta are divided into two groups: women with normal blood loss (BV < 500 ml) versus women with increased blood loss (BV ≥ 500 ml). The clinical data of pregnant women with histologically verified placental disorders, who gave birth in the Women's Clinic University Hospital Basel (USB) between 1986 and 2019, are compared with each other.

NCT ID: NCT05539859 Recruiting - Clinical trials for Intracerebral Hemorrhage Basal Ganglia

Efficacy and Safety of NeuroEndoscopic Surgery for IntraCerebral Hemorrhage

NESICH
Start date: November 18, 2022
Phase: N/A
Study type: Interventional

To compare the efficacy and safety of neuroendoscopic hematoma removal and standard conservative treatment for patients with spontaneous supratentorial deep intracerebral hemorrhage.

NCT ID: NCT05538286 Recruiting - TUSC Clinical Trials

Transcranial Ultrasound Via Sonolucent Cranioplasty After Minimally Invasive Intracerebral Hemorrhage Evacuation

TUSC MIS
Start date: September 23, 2022
Phase: N/A
Study type: Interventional

Postoperative rebleeding is a major limitation of surgical evacuation for intracerebral hemorrhage (ICH). While computed tomography (CT) is the standard of care for postoperative hematoma cavity monitoring, CT requires significant physical and financial costs. Studies have demonstrated varying degrees of efficacy when using transcranial ultrasound to measure ICH volume. Recently, synthetic implants for cranioplasty have been shown to be safe and sonolucent. This study aims to evaluate the ability of transcranial ultrasound with sonolucent cranioplasty (TUSC) to detect and quantify bleeding in postoperative ICH patients.

NCT ID: NCT05532215 Recruiting - Clinical trials for Post Partum Hemorrhage

Sublingual Misoprostol in Reduction of Caesarean Blood Loss

SUMIROCBLOL
Start date: March 14, 2023
Phase: N/A
Study type: Interventional

Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery. Oxytocin use in tropical developing countries for the reduction blood loss at caesarean section have been met with challenges of ineffectiveness due to poor transportation, inadequate storage and drug adulteration. Therefore, there is a need for an effective, temperature stable uterotonic with a lesser risk of adulteration. The study is aimed at evaluating the effectiveness and safety of adjunctive sublingual misoprostol in reducing intraoperative blood loss at caesarean section.

NCT ID: NCT05529589 Recruiting - Vitreous Hemorrhage Clinical Trials

Comparison of Restoration in Vitreous Hemorrhage Patients With DME After or Not Removing Inner Limiting Membrane

Start date: February 10, 2023
Phase:
Study type: Observational

This study is conducted to compare the anti-VEGF effect and visual function in vitreous hemorrhage patients with diabetic macular edema after pars plana vitrectomy with inner limiting membrane peeling or not

NCT ID: NCT05525143 Completed - Clinical trials for Postpartum Hemorrhage

Postpartum Hemorrhage: Incidence and Risk Factors

Start date: October 10, 2022
Phase:
Study type: Observational

Postpartum hemorrhage(PPH) is a major cause of maternal morbidity and mortality across the world. Incidence of PPH varies in the literature from 2 to 10%, most recent studies find around 10% of PPH and 2% of severe PPH. In this study, the incidence of PPH in the maternal ward of the CHU Brugmann will be analyzed. This is a tertiary maternal ward with a high proportion of high risk pregnancies with around 3000 admissions per year. Primary aim of this study is to evaluate the epidemiology of PPH in the CHU Brugmann, incidence and possible underlying causes will be identified and compared to the current literature. A data mining technique will be used to construct a prediction model for PPH.