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Hemorrhage clinical trials

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NCT ID: NCT05949268 Recruiting - Clinical trials for GastroIntestinal Bleeding

Video Capsule Endoscopy for Detection of Gastrointestinal Bleeding in the Small Bowel

Start date: September 1, 2023
Phase:
Study type: Observational

Small bowel capsule endoscopy is the main diagnostic standard for small bowel bleeding. This study investigates the detection rate of small bowel bleeding in capsule endoscopy and further endoscopic treatment in a prospective and retrospective cohort.

NCT ID: NCT05948436 Completed - Clinical trials for Cesarean Section Complications

The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section

Start date: July 10, 2023
Phase: N/A
Study type: Interventional

The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be taken. In this study, we aim to decrease the amount of postpartum hemorrhage by clamping the uterine artery after the delivery of the baby during Cesarean delivery.

NCT ID: NCT05945680 Recruiting - Bleeding Clinical Trials

Tranexamic Acid in Breast Esthetic Surgery.

Start date: September 15, 2023
Phase: Phase 4
Study type: Interventional

The investigators prepared a novel tranexamic acid (TXA) study designed to estimate the quantity of blood loss in patients undergoing breast esthetic surgery. This study aims to quantify blood loss during abdominoplasty with and without TXA. The central hypothesis is that TXA administration reduces blood loss and fibrinolysis in breast esthetic surgery patients.

NCT ID: NCT05942755 Recruiting - Clinical trials for Subarachnoid Hemorrhage

Study of Changes in CSF Ionic Composition After Aneurysmal Meningeal Hemorrhage

ION_SAH
Start date: October 1, 2022
Phase:
Study type: Observational

Hyponatremia is a frequent complication of subarachnoid hemorrhage (SAH) with a prevalence of 30 to 50% in patients with this condition. This hydro-electrolytic disorder is responsible for an increase in morbidity with the appearance of neurological disorders. Also, it has been shown that there are ionic changes in the cerebrospinal fluid and a probable alteration of the blood-brain barrier in patients with SAH. The kinetics and relationship between hyponatremia and these changes remain unknown. The main objective of the study is to determine whether the change in cerebrospinal fluid (CSF) composition, precedes the development of hyponatremia. For this, the investigators propose to study the evolution of the CSF ionogram with the blood ionogram. Furthermore, they will perform additional analyses on the basis of a control group (CSF of patient with normal pressure hydrocephalus) to determine the effect of SAH on ionic changes. The hypothesis of the study is that there is a correlation between the change in CSF blood ionogram and the development of hyponatremia between day 0 and day 14.

NCT ID: NCT05941572 Recruiting - Trauma Injury Clinical Trials

Resuscitative Endovascular Balloon Occlusion of the Aorta in Haemorrhagic Shock

Start date: June 28, 2023
Phase:
Study type: Observational

Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a procedure that has the goal to stabilize trauma patients with non-compressible torso hemorrhage by temporarily occluding the aorta with a ballon catheter to increase central perfusion and stop uncontrollable bleeding from the diaphragm downwards. The investigators are planning to evaluate all patients who had a REBOA catheter placed at their clinic or in the pre-clinical setting from the start of 2019 to the 31.12.2022 who were transferred to their clinic, with basic demographic and clinical data, the procedural specifics, and their potential complications.

NCT ID: NCT05937516 Completed - Epistaxis Nosebleed Clinical Trials

Guidewire Use in Nasotracheal Intubation

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

During nasotracheal intubation, nasopharyngeal trauma and associated bleeding may occur. The investigators think that some of this bleeding is due to trauma to the posterior wall of the nasopharynx. The investigators designed this study, thinking that if nasopharyngeal posterior wall trauma can be prevented, some of these bleedings can be prevented.

NCT ID: NCT05936645 Recruiting - Placenta Accreta Clinical Trials

The Efficacy of a Temporary Sub-Placental Uterine Tourniquet in Minimizing Intraoperative Blood Loss in Management of Placenta Accreta Spectrum Disorder by a Retrograde Cesarean Hysterectomy (Bladder Last)

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

This trial will study the role of a temporary tourniquet around the uterus to reduce blood loss in management of patients with abnormally implanted placenta who will undergo removal of the uterus.

NCT ID: NCT05933135 Active, not recruiting - Clinical trials for Gastro Intestinal Bleeding

Factor XIII Activity in Gastrointestinal Bleedings

Start date: January 8, 2021
Phase:
Study type: Observational

The aim of this retrospective study is to investigate the relationship between factor XIII activity and the outcome of gastrointestinal bleedings. Since factor XIII is of great importance in haemostasis and plays a key role in stabilizing the fibrin clot, it can be assumed that a deficiency of factor XIII leads to an unfavorable course of gastrointestinal bleedings. Our hypothesis is that early detection of such a deficiency can prevent a more severe course and that substitution of factor XIII contributes to faster cessation of bleeding, improves patient outcome and reduces the number of red cell concentrates required.

NCT ID: NCT05932407 Not yet recruiting - Clinical trials for Major Depressive Disorder

A Database Survey of Comparison The Risk of Haemorrhage Between Vortioxetine Tablet Treatment and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment in Participants With Depression

Start date: June 1, 2024
Phase:
Study type: Observational

This study is a retrospective database study in Japan to evaluate the relative risk of serious intracranial hemorrhage requiring hospitalization between Vortioxetine tablet treatment and selective serotonin reuptake inhibitor (SSRI) treatment for patients with depression. This survey will conduct in use of medical database called JMDC claims database.

NCT ID: NCT05929404 Completed - Clinical trials for Bleeding UGI (During or Post-ERCP)

Incidence and Predictors of Bleeding During and Following ERCP

Start date: September 1, 2018
Phase:
Study type: Observational

The incidence of bleeding during ERCP and following ERCP has been estimated using retrospective sources, but granular predictors of bleeding remain unknown, including the use of direct-acting anticoagulants and discontinuation and resumption patterns surrounding their use. In this study, we will aim to assess the incidence and predictors of intra-procedural bleeding during ERCP, and clinically significant post-procedural bleeding following ERCP.