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Clinical Trial Summary

The purpose of the study is to find out whether non-responsiveness to therapeutic recombinant human granulocyte colony-stimulation factor (rhG-CSF) is associated with hemophagocytosis in critically ill adult patients with cytopenias.


Clinical Trial Description

In children with bi- or pancytopenia, hemophagocytosis is known as life-threatening hemophagocytic lymphohistiocytosis (HLH). The purpose of the study is to find out whether adult patients with bicytopenia or pancytopenia fulfilling the clinical HLH criteria used in children reflect life-threatening hemophagocytosis and whether hemophagocytosis is associated with responsiveness to recombinant human granulocyte colony-stimulation factor (rhG-CSF) or not. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01913938
Study type Observational
Source University of Ulm
Contact Manfred E Weiss, MD
Phone 49-731-50060226
Email manfred.weiss@uniklinik-ulm.de
Status Recruiting
Phase
Start date July 2013
Completion date December 2026

See also
  Status Clinical Trial Phase
Completed NCT03546101 - Early Detection of Epstein-Barr Virus Related Disease.
Completed NCT02401932 - Retrospective Analysis for Patients With Hemophagocytosis in Bone Marrow N/A