Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine if a new MR pulse sequence is accurate in determining how much iron is in the liver.


Clinical Trial Description

Quantification of liver iron requires liver biopsy and histological assessment. New rapid MR techniques allow determination of liver relaxation times that can be altered with increasing iron deposition. The purpose of this study is to compare the results obtained with MRI to liver biopsy and iron quantification in patients undergoing liver biopsy in the setting of hemochromatosis. ;


Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT00587535
Study type Observational
Source Mayo Clinic
Contact
Status Completed
Phase N/A
Start date August 2003
Completion date July 2011

See also
  Status Clinical Trial Phase
Completed NCT00199628 - Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
Completed NCT03654794 - Study of the Cellular Diffusion of Tacrolimus Across the Membrane of Mononuclear Cells
Terminated NCT00122980 - Stroke With Transfusions Changing to Hydroxyurea Phase 3
Completed NCT00202436 - Haemochromatosis:Phlebotomy Versus Erythrocytapheresis Therapy Phase 3
Withdrawn NCT01892644 - Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic Syndrome Phase 2
Not yet recruiting NCT01524757 - Proton Pump Inhibitors in the Prevention of Iron Reaccumulation in Patient With Hereditary Hemochromatosis N/A
Completed NCT00349453 - Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients Phase 2
Recruiting NCT03743272 - Repeatability and Reproducibility of Multiparametric MRI
Recruiting NCT06137079 - "Iron Overload and Endocrinological Diseases"
Completed NCT00712738 - Oral Nifedipine to Treat Iron Overload Phase 1
Completed NCT00001455 - Iron Overload in African Americans N/A
Completed NCT00006312 - Hemochromatosis--Genetic Prevalence and Penetrance N/A
Completed NCT00005559 - Statistical Basis for Hemochromatosis Screening N/A
Recruiting NCT00509652 - Erythrocyte Apheresis Versus Phlebotomy in Hemochromatosis N/A
Completed NCT00350662 - Study With Deferiprone and/or Desferrioxamine in Iron Overloaded Patients Phase 3
Completed NCT00005541 - Hemochromatosis and Iron Overload Screening Study (HEIRS) N/A
Completed NCT00000595 - Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis Phase 2
Completed NCT04631718 - MRI QSM Imaging for Iron Overload
Active, not recruiting NCT00007150 - Treatment of Hemochromatosis Phase 2
Enrolling by invitation NCT02025543 - Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron Content