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Hemangioma clinical trials

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NCT ID: NCT03853070 Recruiting - Aneurysm Clinical Trials

Post Market Clinical Follow-Up for ED Coil / Electro-detach Generator v4

Start date: December 11, 2018
Phase:
Study type: Observational

This is a multicenter post-marketing clinical follow-up study to collect safety and performance data in a prospective cohort of patients who will have undergone coil embolization using the ED Coil and ED Detach Generator v4.

NCT ID: NCT03842631 Recruiting - Clinical trials for Infantile Hemangioma

Optimizing Timolol Maleate Treatment of Infantile Hemangioma by Doppler Ultrasound Examination

Start date: February 16, 2019
Phase:
Study type: Observational

The purpose of this study is to assess the safety and efficacy of Timolol Maleate treatment for different depth of infantile hemangioma based on B-ultrasonography. Based on the depth of hemangioma, patients will be proactively allocated to two groups. And then, all patients in both groups will receive topical timolol treatment in the same protocol and dosage.

NCT ID: NCT03774017 Recruiting - Clinical trials for Cerebrovascular Disease

Research on Hybrid Operation Technique in the Treatment of Complex Brain Arteriovenous Malformations

HOTAVM
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Complex brain arteriovenous malformations (bAVMs) in ≥3 Spetzler-Martin grades have long been challenges among cerebrovascular diseases. None of the traditional methods, such as microsurgical operation, endovascular intervention, or stereotactic radiotherapy, can completely eliminate complex bAVMs without a risk of neural function deterioration. The multistaged hybrid operation solved part of the challenge but remained risky in the installment procedures and intervals. The one-staged hybrid operation was applied in the surgical treatment of cerebrovascular diseases and proved to be a potentially safe and effective method for curing complex bAVMs. However, lacking the support of high-level evidence, its advantages remain unclear. This study was proposed to validate the benefits and risks of one-staged hybrid operation in the treatment of complex bAVMs, as well as its indications, key technologies, and workflows.

NCT ID: NCT03676868 Recruiting - Clinical trials for Cerebral Arteriovenous Malformations

Biology of Cerebral Arteriovenous Malformations and Prognosis of Cerebral Arteriovenous Malformations

BioMAV
Start date: November 20, 2018
Phase:
Study type: Observational

The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation. The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke. The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.

NCT ID: NCT03633747 Recruiting - Hemangioma Liver Clinical Trials

Efficacy Evaluation of Propranolol Treatment of Hepatic Hemangioma

Start date: July 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Hepatic hemangioma is one of the most common benign tumor of the liver. Although the overall prognosis is good, active interventions are still needed in high-risk patients. Without specific drugs, the main treatment methods include surgical treatments, interventional therapies and radiotherapies. Effective medical treatments are needed urgently. Propranolol has achieved good results in infantile Facial/hepatic hemangioma, and shows some effectiveness in adult hemangioma. Here, investigators intend to evaluate the therapeutic effect of propranolol in adult hepatic hemangioma.

NCT ID: NCT03571282 Recruiting - Clinical trials for Circumscribed Choroidal Haemangioma

Safety and Effectiveness of Intravitreal Conbercept for Exudative Circumscribed Choroidal Haemangioma

Start date: June 6, 2018
Phase: Early Phase 1
Study type: Interventional

This prospective clinical trial aims to evaluate the safety and effectiveness study of intravitreal conbercept injection for exudative circumscribed choroidal haemangioma.

NCT ID: NCT03516162 Recruiting - Brain Tumor Clinical Trials

Linking Digital Smartphone Behaviour With Brain Function

SmartSurgery
Start date: April 20, 2018
Phase:
Study type: Observational

This study will thus examine daily behaviour based on smartphone use and link it to the neurological and neuropsychological status as well as to neuroradiological studies that are part of the clinical routine. The study will examine behaviour changes before and after surgery, and how this change in measured behaviour with the smartphone relates to today's "gold standard", namely professional neuropsychological examination and quantification of brain damage on imaging studies (MRI). This study is a proof-of-principle study that intends to build the basis for larger future observational studies on patients with focal or diffuse brain pathologies.

NCT ID: NCT03367975 Recruiting - Clinical trials for Subarachnoid Hemorrhage

NIRS Monitoring During Intracranial Interventions

NIRS_ICG
Start date: March 2014
Phase: N/A
Study type: Observational

Near infrared spectroscopy is a valuable tool to monitor cerebral oxygenation during intracranial interventions. However, it yields artificial results when the dye indocyanine green (ICG) is applied, which is routinely done for intraoperative angiography. The investigators examine, to what extent and which duration NIRS is disturbed following ICG application.

NCT ID: NCT03331744 Recruiting - Hemangioma Clinical Trials

Clinical Characteristics of Infantile Hemangioma

Start date: October 6, 2017
Phase:
Study type: Observational [Patient Registry]

The primary purpose of this study is to identify the clinical characteristics of infantile hemangioma (IH) in our single center in China. The second objective of the study is to identify the clinical features of infantile hepatic hemangioma (IHH) and ulceration in patients with IHs.

NCT ID: NCT03306836 Recruiting - Cerebral Aneurysm Clinical Trials

Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2

EAPCAAMHO2
Start date: September 2016
Phase: N/A
Study type: Interventional

In the stage of randomized controlled study, our purpose is to obtain the Intraoperative anticoagulation program supported by evidence-based medicine.