Doxycycline for Helicobacter Pylori Rescue Treatment

Status Recruiting

Clinical Trial Summary

Current guidelines have recommended classical bismuth-containing quadruple therapy including proton-pump inhibitor, bismuth, tetracycline, metronidazole as the empirical rescue therapy. However, tetracycline is clinically unavailable in China and the high frequency of adverse events of bismuth quadruple therapy often result in poor compliance, which limited the applicability of this recommendation. This study aimed to compare the efficacy and tolerability of a 14-day bismuth-containing quadruple rescue therapy in which tetracycline was replaced by doxycycline.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Helicobacter Pylori Infection

Clinical Trial Details

NCT number	NCT05874570
Study type	Interventional
Source	Shanghai Jiao Tong University School of Medicine
Contact
Status	Recruiting
Phase	Phase 4
Start date	June 20, 2023
Completion date	December 31, 2024

View Details

See also
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